Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Aortic Dilatation on the Edge of Dissection – Do We Operate Too Late? The Ratio between Ascending and Descending Aorta DiameteR (RADAR)

Nerea Lopez Perez
* ,
Philippe Reymond
,
Mustafa Cikirikcioglu
ORCID logo ,
Mathieu Van Steenberghe
,
Tornike Sologashvili
,
Nicolas Murith
,
Thomas Perneger
,
Christoph Huber
* ORCID logo
Version 1 : Received: 24 May 2023 / Approved: 25 May 2023 / Online: 25 May 2023 (13:00:28 CEST)

A peer-reviewed article of this Preprint also exists.

Lopez Perez, N.; Reymond, P.; Cikirikcioglu, M.; van Steenberghe, M.; Sologashvili, T.; Murith, N.; Perneger, T.; Huber, C. Aortic Dilatation on the Edge of Dissection––Do We Operate Too Late? The Ratio between Ascending and Descending Aorta DiameteR (RADAR). J. Clin. Med. 2023, 12, 4400. Lopez Perez, N.; Reymond, P.; Cikirikcioglu, M.; van Steenberghe, M.; Sologashvili, T.; Murith, N.; Perneger, T.; Huber, C. Aortic Dilatation on the Edge of Dissection––Do We Operate Too Late? The Ratio between Ascending and Descending Aorta DiameteR (RADAR). J. Clin. Med. 2023, 12, 4400.

Abstract

(1) Background: There is a need of a novel surrogate marker to ease decision making when facing ascending aortic dilatation. In this article we study the ratio between ascending and descending aorta diameters as a potential one; (2) Methods: Retrospective observational cohort study, including all the patients who have undergone surgery for aTAAD between January 2014 and September 2020 at our center. A total of 50 patients were included. Clinical and demographic data was collected. Anatomical measurements were made including orthogonal maximal diameters of the ascending and descending aorta, post-dissection whole circumference length (post-wCL), post-dissection true lumen circumference length (post-tCL), surface and sphericity index of the ascending and descending aorta. Pre-dissection ascending aorta diameter (pre-AAD) and pre-dissection descending aorta diameter (pre-DAD) were calculated as well as the ratio between them and compared with reference values; (3) Results: 96% of the patients pre-AAD was smaller than the recommended 55mm. The ratio between the descending and ascending aorta pre-dissection diameters was significantly smaller compared to the reference value (0.657±0.125 versus 0.745± 0.016 with a mean difference of -0.088 and a p<0.001); (4) Conclusions: The 55mm threshold for aorta maximal diameter is an insufficient criterion when assessing the risk of dissection. The ratio between DAD and AAD is a parameter worthy of analysis as a tool to stratify the risk of dissection.

Keywords

cardiac surgery; ascending aorta dissection, ascending aorta aneurysm

Subject

Medicine and Pharmacology, Cardiac and Cardiovascular Systems

Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Download PDF

Comments (0)

We encourage comments and feedback from a broad range of readers. See criteria for comments and our Diversity statement.

Leave a public comment
Send a private comment to the author(s)
* All users must log in before leaving a comment
Views 0
Downloads 0
Comments 0
Metrics 0
Get PDF Cite Share 0
Bookmark BibSonomy Mendeley Reddit Delicious
×
Alerts
Notify me about updates to this article or when a peer-reviewed version is published.
We use cookies on our website to ensure you get the best experience.
Read more about our cookies here.