Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Application of Heisenberg’s Uncertainty Principle in the Diag-Nostic Dilemma of Children With Acute Appendicitis: Negative Appendectomy Versus Complicated Appendicitis Rates

Version 1 : Received: 22 May 2023 / Approved: 23 May 2023 / Online: 23 May 2023 (04:58:36 CEST)

How to cite: Roupakias, S.; Fouzas, S.; Kostopoulou, E.; Gkentzi, D.; Dassios, T.; Spyridakis, I.; Sinopidis, X. Application of Heisenberg’s Uncertainty Principle in the Diag-Nostic Dilemma of Children With Acute Appendicitis: Negative Appendectomy Versus Complicated Appendicitis Rates. Preprints 2023, 2023051575. https://doi.org/10.20944/preprints202305.1575.v1 Roupakias, S.; Fouzas, S.; Kostopoulou, E.; Gkentzi, D.; Dassios, T.; Spyridakis, I.; Sinopidis, X. Application of Heisenberg’s Uncertainty Principle in the Diag-Nostic Dilemma of Children With Acute Appendicitis: Negative Appendectomy Versus Complicated Appendicitis Rates. Preprints 2023, 2023051575. https://doi.org/10.20944/preprints202305.1575.v1

Abstract

Abstract Background. There is an inherent limit in the accuracy of our measurements, set by nature itself and predicted by Heisenberg's uncertainty principle, which defines the properties of nature in the microcosmos. There is a fundamental limit to the accuracy with which complementary phys-ical quantities of a particle can be predicted from their initial conditions. As classical physics is essentially considered at borderline of quantum mechanics, so the power of uncertainty princi-ple is limited in describing everyday life perceived or managed phenomena. Method. In this study, we apply Heisenberg's uncertainty principle to children under diagnostic uncertainty re-garding appendicitis. We analyze this phenomenon in clinical practice. Results. Medical practice is full of uncertainty. False negative decisions correlate with delays in treatment and adverse outcomes in children with atypical appendicitis. On the other hand, false-positive surgery deci-sions result in negative appendectomies. With improvement of technology, the incidence of complicated appendicitis or negative appendectomies due to diagnostic uncertainty has de-creased but cannot be ignored or eliminated. Conclusion. According to the principle, there is a fundamental limit to the accuracy with which the complementary variables of negative appen-dectomy and complicated appendicitis can be observed or measured simultaneously. What does all this mean for the physician?

Keywords

complicated appendicitis; negative appendectomy; Heisenberg’s principle; diagnostic uncertainty; children

Subject

Medicine and Pharmacology, Surgery

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