Version 1
: Received: 15 May 2023 / Approved: 16 May 2023 / Online: 16 May 2023 (08:28:45 CEST)
How to cite:
Tama, A.; Pieńkowska, N.; Stefaniuk, I.; Bartosz, G.; Sadowska-Bartosz, I. Hydrogen Peroxide Is a Component of Infusions of Medicinal Herbs. Preprints2023, 2023051125. https://doi.org/10.20944/preprints202305.1125.v1
Tama, A.; Pieńkowska, N.; Stefaniuk, I.; Bartosz, G.; Sadowska-Bartosz, I. Hydrogen Peroxide Is a Component of Infusions of Medicinal Herbs. Preprints 2023, 2023051125. https://doi.org/10.20944/preprints202305.1125.v1
Tama, A.; Pieńkowska, N.; Stefaniuk, I.; Bartosz, G.; Sadowska-Bartosz, I. Hydrogen Peroxide Is a Component of Infusions of Medicinal Herbs. Preprints2023, 2023051125. https://doi.org/10.20944/preprints202305.1125.v1
APA Style
Tama, A., Pieńkowska, N., Stefaniuk, I., Bartosz, G., & Sadowska-Bartosz, I. (2023). Hydrogen Peroxide Is a Component of Infusions of Medicinal Herbs. Preprints. https://doi.org/10.20944/preprints202305.1125.v1
Chicago/Turabian Style
Tama, A., Grzegorz Bartosz and Izabela Sadowska-Bartosz. 2023 "Hydrogen Peroxide Is a Component of Infusions of Medicinal Herbs" Preprints. https://doi.org/10.20944/preprints202305.1125.v1
Abstract
The aim of this study was to examine whether H2O2, generated in such beverages as tea and coffee, is formed also in infusions of medicinal herbs and propose the possible mechanism of its formation. Infusions of sixteen herbs were studied and the presence of H2O2 was found in all cases. The highest concentrations of H2O2, exceeding 50 µM, were found in the infusions of leaves of Betula and Polygonum, and of the inflorescence of Tilia. These low amounts of H2O2 should not have a harmful effect and may even exert beneficial action, perhaps contributing to the health effects of the herbs. Generation of semiquinone and superoxide radicals was detected in herbal infusions, indicating that oxidation of phenolic compounds is the main source of H2O2 in these infusions. Herbal infusions were cytotoxic to human ovary cancer SKOV-3 and PEO1 cells; this cytotoxicity was compromised by catalase added to the growth medium, demonstrating the contribution of hydrogen peroxide to the cytotoxic action of herbal extracts.
Keywords
hydrogen peroxide; FOX assay; medicinal herbs; ovary cancer cells; polyphenols
Subject
Biology and Life Sciences, Food Science and Technology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
