Huang, J.-B.; Huang, K.-C.; Hsieh, T.-M.; Tsai, C.-M.; Hsiao, H.-Y.; Cheng, C.-Y.; Cheng, F.-J. Association between Air Pollution and Short-Term Outcome of ST-Segment Elevation Myocardial Infarction in a Tropical City, Kaohsiung, Taiwan. Toxics2023, 11, 541.
Huang, J.-B.; Huang, K.-C.; Hsieh, T.-M.; Tsai, C.-M.; Hsiao, H.-Y.; Cheng, C.-Y.; Cheng, F.-J. Association between Air Pollution and Short-Term Outcome of ST-Segment Elevation Myocardial Infarction in a Tropical City, Kaohsiung, Taiwan. Toxics 2023, 11, 541.
Huang, J.-B.; Huang, K.-C.; Hsieh, T.-M.; Tsai, C.-M.; Hsiao, H.-Y.; Cheng, C.-Y.; Cheng, F.-J. Association between Air Pollution and Short-Term Outcome of ST-Segment Elevation Myocardial Infarction in a Tropical City, Kaohsiung, Taiwan. Toxics2023, 11, 541.
Huang, J.-B.; Huang, K.-C.; Hsieh, T.-M.; Tsai, C.-M.; Hsiao, H.-Y.; Cheng, C.-Y.; Cheng, F.-J. Association between Air Pollution and Short-Term Outcome of ST-Segment Elevation Myocardial Infarction in a Tropical City, Kaohsiung, Taiwan. Toxics 2023, 11, 541.
Abstract
ST-segment elevation myocardial infarction (STEMI), a major cause of mortality worldwide, has been shown through epidemiological studies to have a relationship with short-term exposure to air pollutants; however, the association between air pollutants and the outcome of STEMI has not been well studied. The aim of this study was to estimate the impact of air pollutants on the outcomes of STEMI. Data on particulate matter <2.5 μm (PM2.5), <10 μm (PM10), nitrogen dioxide (NO2), and ozone (O3) at each of the 11 air monitoring stations in Kaohsiung City were collected between January 1, 2012, and December 31, 2017. Medical records of non-trauma patients aged > 20 years who had visited the ED with a principal diagnosis of STEMI were extracted. The primary outcome measure was in-hospital mortality. After adjusting for potential confounders and meteorological variables, we found that an increase in the interquartile range (IQR) in NO2 was associated with an elevated risk of in-hospital mortality in patients with STEMI. Moreover, during the warm season, an IQR increase in NO2 corresponded to a higher risk of in-hospital mortality in patients with STEMI on lag 3 (OR=3.266; 95% CI:1.203–8.864, p=0.02). Conversely, an IQR increase in PM10 was associated with an increased risk of in-hospital mortality in patients with STEMI on lag 3 (OR=2.792; 95%CI:1.115–6.993, p=0.028) during the cold season. Our study suggests that exposure to NO2 (during warm season) and PM10 (during cold season) may contribute to a higher risk of poor prognosis in patients with STEMI.
Public Health and Healthcare, Public, Environmental and Occupational Health
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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