Alsharairi, N.A. Antioxidant Intake and Biomarkers of Asthma in Relation to Smoking Status—A Review. Current Issues in Molecular Biology 2023, 45, 5099–5117, doi:10.3390/cimb45060324.
Alsharairi, N.A. Antioxidant Intake and Biomarkers of Asthma in Relation to Smoking Status—A Review. Current Issues in Molecular Biology 2023, 45, 5099–5117, doi:10.3390/cimb45060324.
Alsharairi, N.A. Antioxidant Intake and Biomarkers of Asthma in Relation to Smoking Status—A Review. Current Issues in Molecular Biology 2023, 45, 5099–5117, doi:10.3390/cimb45060324.
Alsharairi, N.A. Antioxidant Intake and Biomarkers of Asthma in Relation to Smoking Status—A Review. Current Issues in Molecular Biology 2023, 45, 5099–5117, doi:10.3390/cimb45060324.
Abstract
Bronchial asthma (BA) is considered a chronic inflammatory disorder associated with airway hyperresponsiveness (AHR). Increased oxidative stress (OS) is a clinical feature of BA, which promotes the inflammatory responses in bronchial/airway epithelial cells. Smokers and nonsmokers with asthma have been shown to have increases in several OS and inflammatory biomarkers. A few studies suggest a relationship between antioxidant intake from diet/supplements and BA in smoking and nonsmoking asthmatics. Dietary carotenoids and vitamin C (VC) intake might reduce BA risk in smokers and/or non-smokers. Evidence is lacking on the protective role of antioxidant vitamin and/or mineral consumption against BA in smokers and nonsmokers with respect to inflammation and OS biomarkers. Therefore, the aim of this review is to highlight current knowledge regarding the relations between antioxidant intake, BA and its associated biomarkers in smokers and nonsmokers.
Medicine and Pharmacology, Dietetics and Nutrition
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