Version 1
: Received: 5 May 2023 / Approved: 6 May 2023 / Online: 6 May 2023 (08:45:06 CEST)
How to cite:
Sierzputowski, C.; Ferrol, M.; Pardillo, M.; LaVarco, A.; Zorns, S.; Keenan, J. P. Stop Eating Brain: The Role of the Cerebellum in Satiation. Preprints2023, 2023050394. https://doi.org/10.20944/preprints202305.0394.v1
Sierzputowski, C.; Ferrol, M.; Pardillo, M.; LaVarco, A.; Zorns, S.; Keenan, J. P. Stop Eating Brain: The Role of the Cerebellum in Satiation. Preprints 2023, 2023050394. https://doi.org/10.20944/preprints202305.0394.v1
Sierzputowski, C.; Ferrol, M.; Pardillo, M.; LaVarco, A.; Zorns, S.; Keenan, J. P. Stop Eating Brain: The Role of the Cerebellum in Satiation. Preprints2023, 2023050394. https://doi.org/10.20944/preprints202305.0394.v1
APA Style
Sierzputowski, C., Ferrol, M., Pardillo, M., LaVarco, A., Zorns, S., & Keenan, J. P. (2023). Stop Eating Brain: The Role of the Cerebellum in Satiation. Preprints. https://doi.org/10.20944/preprints202305.0394.v1
Chicago/Turabian Style
Sierzputowski, C., Samantha Zorns and Julian Paul Keenan. 2023 "Stop Eating Brain: The Role of the Cerebellum in Satiation" Preprints. https://doi.org/10.20944/preprints202305.0394.v1
Abstract
Decades of research have indicated that that the hypothalamus is responsible for multiple aspects of appetitive behavior. However, recent neuroimaging studies have led researchers to believe that the cerebellum may also serve a function in the regulation of appetite and satiation. Here we aim to identify, through the use of transcranial magnetic stimulation, or TMS, whether the inhibition of the cerebellum influences appetite in healthy participants. We hypothesized that inhibitory TMS, delivered to the cerebellum, would cause the participants to have an increase in appetite, resulting in overeating and a reduction in satiation. It was found that inhibitory TMS delivered to the cerebellar region increased consumption of high fat and calorie foods. These data support the previous research suggesting a cerebellar role in appetite. We propose that this and related studies may eventuate in a new alternative treatment option for those struggling with obesity and various other genetic disorders that cause overeating.
Keywords
Cerebellum; Satiation; Transcranial Magnetic Stimulation; TMS
Subject
Biology and Life Sciences, Neuroscience and Neurology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
