Version 1
: Received: 3 May 2023 / Approved: 4 May 2023 / Online: 4 May 2023 (04:22:34 CEST)
How to cite:
Konic Ristic, A.; Ryan, S.; Attjioui, M.; O’Connell, S.; R. Gibney, E. Effects of an Extract of the Brown Seaweed Ascophylum nodosum on Postprandial Glycaemic Control in Healthy Subjects: A Randomized Controlled Study. Preprints2023, 2023050187. https://doi.org/10.20944/preprints202305.0187.v1
Konic Ristic, A.; Ryan, S.; Attjioui, M.; O’Connell, S.; R. Gibney, E. Effects of an Extract of the Brown Seaweed Ascophylum nodosum on Postprandial Glycaemic Control in Healthy Subjects: A Randomized Controlled Study. Preprints 2023, 2023050187. https://doi.org/10.20944/preprints202305.0187.v1
Konic Ristic, A.; Ryan, S.; Attjioui, M.; O’Connell, S.; R. Gibney, E. Effects of an Extract of the Brown Seaweed Ascophylum nodosum on Postprandial Glycaemic Control in Healthy Subjects: A Randomized Controlled Study. Preprints2023, 2023050187. https://doi.org/10.20944/preprints202305.0187.v1
APA Style
Konic Ristic, A., Ryan, S., Attjioui, M., O’Connell, S., & R. Gibney, E. (2023). Effects of an Extract of the Brown Seaweed <em>Ascophylum nodosum</em> on Postprandial Glycaemic Control in Healthy Subjects: A Randomized Controlled Study. Preprints. https://doi.org/10.20944/preprints202305.0187.v1
Chicago/Turabian Style
Konic Ristic, A., Shane O’Connell and Eileen R. Gibney. 2023 "Effects of an Extract of the Brown Seaweed <em>Ascophylum nodosum</em> on Postprandial Glycaemic Control in Healthy Subjects: A Randomized Controlled Study" Preprints. https://doi.org/10.20944/preprints202305.0187.v1
Abstract
The effects of the consumption of an extract of the brown seaweed Ascophyllum nodosum (BSW) on postprandial glucose and insulin response to white bread were investigated in an acute, randomized, double-blind, three-arm, crossover, controlled trial in healthy, normoglyacemic subjects. Sixteen subjects were administrated either control white bread (50 g total digestible carbohydrates), or white bread with either 500 mg or 1000 mg of BSW extract. Biochemical parameters were measured in venous blood over 3h. Significant inter-individual variation in the glycaemic response to white bread was observed. Analysis of the response of all subjects to either 500 mg or 1000 mg of BSW extract versus control revealed no significant effects of treatments. The variation in response to the control was used to classify individuals into glyacemic responders and non-responders. In the sub-cohort of 10 subjects with peak glucose levels after white bread above 1mmol/L we observed a significant decrease in maximum levels of plasma glucose after the intervention meal with 1000 mg of extract, compared with control. No adverse effects were reported. Further work defining all factors that determine “responders” to the effects of brown seaweed extracts and identify the cohort that would benefit the most from their consumption, is warranted.
Medicine and Pharmacology, Dietetics and Nutrition
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
