Staubli, S.M.; Ceresa, C.D.L.; Pollok, J.M. The Current Role and Future Applications of Machine Perfusion in Liver Transplantation. Bioengineering2023, 10, 593.
Staubli, S.M.; Ceresa, C.D.L.; Pollok, J.M. The Current Role and Future Applications of Machine Perfusion in Liver Transplantation. Bioengineering 2023, 10, 593.
Staubli, S.M.; Ceresa, C.D.L.; Pollok, J.M. The Current Role and Future Applications of Machine Perfusion in Liver Transplantation. Bioengineering2023, 10, 593.
Staubli, S.M.; Ceresa, C.D.L.; Pollok, J.M. The Current Role and Future Applications of Machine Perfusion in Liver Transplantation. Bioengineering 2023, 10, 593.
Abstract
The relative paucity of donor livers suitable for transplantation has sparked innovations to preserve and recondition organs to expand the pool of transplantable organs. Currently, machine perfusion techniques have led to the improvement of the quality of marginal livers and to prolonged cold ischemia time and allowed for the prediction of graft function through analysis of the organ during perfusion, improving the rate of organ use. In the future, the implementation of organ modulation might expand the scope of machine perfusion beyond its current usage. The aim of this review was to provide an overview of the current clinical use of machine perfusion devices in liver transplantation and provide a perspective for future clinical use, including therapeutic interventions in perfused donor liver grafts.
Keywords
Liver transplantation; organ perfusion
Subject
Medicine and Pharmacology, Dermatology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
