Version 1
: Received: 16 February 2023 / Approved: 20 February 2023 / Online: 20 February 2023 (08:59:03 CET)
How to cite:
Gao, Y.; Qin, D.; Shen, Y.; Jian, L.; Gu, P. Antioxidant and Potential Non-antioxidant Roles of Vitamin E in Reproduction of Male Domestic Animals. Preprints2023, 2023020333. https://doi.org/10.20944/preprints202302.0333.v1
Gao, Y.; Qin, D.; Shen, Y.; Jian, L.; Gu, P. Antioxidant and Potential Non-antioxidant Roles of Vitamin E in Reproduction of Male Domestic Animals. Preprints 2023, 2023020333. https://doi.org/10.20944/preprints202302.0333.v1
Gao, Y.; Qin, D.; Shen, Y.; Jian, L.; Gu, P. Antioxidant and Potential Non-antioxidant Roles of Vitamin E in Reproduction of Male Domestic Animals. Preprints2023, 2023020333. https://doi.org/10.20944/preprints202302.0333.v1
APA Style
Gao, Y., Qin, D., Shen, Y., Jian, L., & Gu, P. (2023). <strong>Antioxidant and Potential Non-antioxidant Roles of Vitamin E in Reproduction of Male Domestic Animals</strong>. Preprints. https://doi.org/10.20944/preprints202302.0333.v1
Chicago/Turabian Style
Gao, Y., Luyang Jian and Peilun Gu. 2023 "<strong>Antioxidant and Potential Non-antioxidant Roles of Vitamin E in Reproduction of Male Domestic Animals</strong>" Preprints. https://doi.org/10.20944/preprints202302.0333.v1
Abstract
Vitamin E facilitates testicular development and semen quality in farm animal. And most research tends to investigate antioxidant roles of Vitamin E in reproductive health; some research also find potential non-antioxidant roles of Vitamin E. To further uncover the mechanism by which Vitamin E modulates reproductive health, the paper reviews specific function of Vitamin E and candidate genes involved in male reproductive performance promoted by Vitamin E. The review found that cell proliferation (PDPN, BMP, Myc, AMPKa, GSK3β, PPARγ, CDK4, CDK6, Ki67, PCNA, Cyclin A2, Cyclin B1, Cyclin B3, BLM, REL, KLHL25)-, cell apoptosis (BCL-2, Caspase 9, Bax)-, spermatogenesis (CatSper1, CatSper2, NDRG1, CYP26B1, FSCN3, FLNA, SPCS3, YBX3, RARS)-, hormone receptor (PGR, FSHR, AR)-related genes are the underlying key points. And two miRNAs, miR-107 and miR-493-3p, which mediate cell cycle process, are also identified in response to Vitamin E treatment. The paper paves the way for a comprehensive understanding about effect of Vitamin E on testis development and semen quality in domestic animals.
Biology and Life Sciences, Animal Science, Veterinary Science and Zoology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
