Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Dynamic Vascular Imaging Using Active Breast Thermography

Version 1 : Received: 12 February 2023 / Approved: 16 February 2023 / Online: 16 February 2023 (06:32:33 CET)

A peer-reviewed article of this Preprint also exists.

Gershenson, M.; Gershenson, J. Dynamic Vascular Imaging Using Active Breast Thermography. Sensors 2023, 23, 3012. Gershenson, M.; Gershenson, J. Dynamic Vascular Imaging Using Active Breast Thermography. Sensors 2023, 23, 3012.

Abstract

Mammography is the gold standard for breast cancer screening and diagnostic imaging; however, there is an unmet clinical need for complementary methods to detect lesions not characterized by mammography. Far-infrared 'thermogram' breast imaging can map the skin temperature, and signal inversion with components analysis can be used to identify the mechanisms of thermal image generation of the vasculature using dynamic thermal data. This work focuses on using dynamic infrared breast imaging to identify the thermal response of the stationary vascular system and the physiologic vascular response to a temperature stimulus affected by vasomodulation. The recorded data is analyzed by converting the diffusive heat propagation into a virtual wave and identifying the reflection using component analysis. Clear images of passive thermal reflection and thermal response to vasomodulation were obtained. Validation of this proposed paradigm through further clinical exploration may demonstrate clinical utility for the IR modality in diagnostic imaging, offering a potential solution to the current unmet clinical need.

Keywords

Breast cancer; components analysis; dynamic thermogram; vasomodulation; veins; virtual wave; equivalent wave field

Subject

Medicine and Pharmacology, Oncology and Oncogenics

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