Version 1
: Received: 30 December 2022 / Approved: 3 January 2023 / Online: 3 January 2023 (08:04:14 CET)
How to cite:
Naghynajadfard, M.; Li, Y. Recovery in Transplanted Rat after Stopping the Injected of Immunosuppressant Agent ‘Cyclosporine’. Preprints2023, 2023010017. https://doi.org/10.20944/preprints202301.0017.v1
Naghynajadfard, M.; Li, Y. Recovery in Transplanted Rat after Stopping the Injected of Immunosuppressant Agent ‘Cyclosporine’. Preprints 2023, 2023010017. https://doi.org/10.20944/preprints202301.0017.v1
Naghynajadfard, M.; Li, Y. Recovery in Transplanted Rat after Stopping the Injected of Immunosuppressant Agent ‘Cyclosporine’. Preprints2023, 2023010017. https://doi.org/10.20944/preprints202301.0017.v1
APA Style
Naghynajadfard, M., & Li, Y. (2023). Recovery in Transplanted Rat after Stopping the Injected of Immunosuppressant Agent ‘Cyclosporine’. Preprints. https://doi.org/10.20944/preprints202301.0017.v1
Chicago/Turabian Style
Naghynajadfard, M. and Ying Li. 2023 "Recovery in Transplanted Rat after Stopping the Injected of Immunosuppressant Agent ‘Cyclosporine’" Preprints. https://doi.org/10.20944/preprints202301.0017.v1
Abstract
The hitologiy image of mouse xenograft of olfactory ensheating cells ( OECs) in to Albino Swiss Strain rats corticospinal tract lesion shows immunorejection after 10 days in grafted tissue . Moreover, the images of postoperative xenotransplanted OECs under daily subcutaneous injection of 100 ml of a dosage of 6 mg/kg/day avoid immunorejection in the misplace of GFP labeled transplanted OECs with the survival time of 4 weeks and there is no sign of inflammation. the result shows that the daily injection of 100ml diluted cyclosporine avoids immune attack and reduces inflammatory cells infiltrate in delayed CST ipsilateral rat model and also our study proved that stop of cyclosporine injection would not prevent DFR function and the regenerated fibers can still be visualised.
Keywords
AS rat, xenotransplant, cyclosporine, GFP
Subject
Biology and Life Sciences, Cell and Developmental Biology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
