Preprint Review Version 2 Preserved in Portico This version is not peer-reviewed

Mass Spectrometry-Based Techniques Towards OMICS 2.0

Version 1 : Received: 29 December 2022 / Approved: 30 December 2022 / Online: 30 December 2022 (08:31:29 CET)
Version 2 : Received: 26 January 2023 / Approved: 27 January 2023 / Online: 27 January 2023 (06:59:30 CET)

How to cite: Šoša, I. Mass Spectrometry-Based Techniques Towards OMICS 2.0. Preprints 2022, 2022120574. Šoša, I. Mass Spectrometry-Based Techniques Towards OMICS 2.0. Preprints 2022, 2022120574.


The literature was scoped to help place mass spectrometric (MS) platforms in the spotlight of the life sciences, as a tool of OMICS and OMICS 2.0 technologies. Moreover, today’s appliances are so handy, that they literally place a whole lab on a single chip. Methods of OMICS (and the most recently developed term OMICS 2.0) are tackled, having in mind their aptness for educational purposes, as well as their feasibility. This same topic was highlighted in many reviews that have been periodically published. The author’s initial interest was the forensic application of MS, but since these interests changed, terms such as “biosensors” were also examined, so the review included means of discovery of efficient biomarkers and clinical therapeutic targets. Aside from simply reviewing the research status and the future perspectives, this article tackles terms such as Society 5.0 and OMICS 2.0. However, within the framework of this review, physical chemistry, bioinformatics, or specific software solutions were not specifically studied. Since the topic of generating permanent collections of digital content for retrospective analysis was also reviewed, the need for loads of data – cloud storage was discussed in the context of MS. These large quantities of data are easier to operate with if generated by MS, rather than by any other commercially available assay. In this manner, the review has strengthened an in-depth understanding of the applications of MS.


cost; mass spectrometry; OMICS; OMICS 2.0: Society 5.0


Medicine and Pharmacology, Pharmacology and Toxicology

Comments (1)

Comment 1
Received: 27 January 2023
Commenter: Ivan Sosa
Commenter's Conflict of Interests: Author
Comment: MS has been brought in line with the new journal, and remodelled to fit in the field of education. 
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