Bushra; Rehman, K.U.; Khan, D.; Almehizia, A.A.; Naglah, A.M.; Al-Wasidi, A.S.; Refat, M.S.; El-Sayed, M.Y.; Ullah, H.; Khan, S. Isolation and Bioassay of a New Terminalone A from Terminalia arjuna. Molecules2023, 28, 1015.
Bushra; Rehman, K.U.; Khan, D.; Almehizia, A.A.; Naglah, A.M.; Al-Wasidi, A.S.; Refat, M.S.; El-Sayed, M.Y.; Ullah, H.; Khan, S. Isolation and Bioassay of a New Terminalone A from Terminalia arjuna. Molecules 2023, 28, 1015.
Bushra; Rehman, K.U.; Khan, D.; Almehizia, A.A.; Naglah, A.M.; Al-Wasidi, A.S.; Refat, M.S.; El-Sayed, M.Y.; Ullah, H.; Khan, S. Isolation and Bioassay of a New Terminalone A from Terminalia arjuna. Molecules2023, 28, 1015.
Bushra; Rehman, K.U.; Khan, D.; Almehizia, A.A.; Naglah, A.M.; Al-Wasidi, A.S.; Refat, M.S.; El-Sayed, M.Y.; Ullah, H.; Khan, S. Isolation and Bioassay of a New Terminalone A from Terminalia arjuna. Molecules 2023, 28, 1015.
Abstract
Terminalia arjuna possesses significant cardio protective, antidiabetic and antioxidant properties as these properties are described in Ayurveda. In the present study, three flavonoids were isolated through the separation and chromatographic purification of the whole plant material of T. arjuna. Spectroscopic characterization identified one of them as a new flavonoid “Terminalone A (1)” and two known flavonoids i.e. 6-hydroxy-2-(4-hydroxyphenyl)-7-methoxy-4H-chromen-4-one (2) and 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one (3). The bioactivity studies showed considerable antibacterial and antioxidant (DPPH was used as a scavenger) potential for all the three compounds 1-3 where the compound 1 showed strong antibacterial and antioxidant activity.
Keywords
Terminalia arjuna; Terminalone A; flavonoids; antibacterial; antioxidants; reactive oxygen specie
Subject
Chemistry and Materials Science, Organic Chemistry
Copyright:
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