Version 1
: Received: 2 November 2022 / Approved: 7 November 2022 / Online: 7 November 2022 (01:15:17 CET)
How to cite:
Bulur, A.; Yumuşatan, P. Disease Severity and Prognostic Nutritional Index (PNI), C-Reactive Protein (CRP), and Red Blood Cell Distribution Width (RDW) in Acute Pancreatitis. Preprints2022, 2022110097. https://doi.org/10.20944/preprints202211.0097.v1
Bulur, A.; Yumuşatan, P. Disease Severity and Prognostic Nutritional Index (PNI), C-Reactive Protein (CRP), and Red Blood Cell Distribution Width (RDW) in Acute Pancreatitis. Preprints 2022, 2022110097. https://doi.org/10.20944/preprints202211.0097.v1
Bulur, A.; Yumuşatan, P. Disease Severity and Prognostic Nutritional Index (PNI), C-Reactive Protein (CRP), and Red Blood Cell Distribution Width (RDW) in Acute Pancreatitis. Preprints2022, 2022110097. https://doi.org/10.20944/preprints202211.0097.v1
APA Style
Bulur, A., & Yumuşatan, P. (2022). Disease Severity and Prognostic Nutritional Index (PNI), C-Reactive Protein (CRP), and Red Blood Cell Distribution Width (RDW) in Acute Pancreatitis. Preprints. https://doi.org/10.20944/preprints202211.0097.v1
Chicago/Turabian Style
Bulur, A. and Pembegül Yumuşatan. 2022 "Disease Severity and Prognostic Nutritional Index (PNI), C-Reactive Protein (CRP), and Red Blood Cell Distribution Width (RDW) in Acute Pancreatitis" Preprints. https://doi.org/10.20944/preprints202211.0097.v1
Abstract
Background: Acute pancreatitis is a common emergency. Morbidity control requires early detection of disease severity. METHODS: A total of 131 AP patients were analyzed retrospectively. Patients were divided into two groups mild AP (MAP: Ranson score <3) and severe AP (SAP: Ranson score ≥3), according to Ranson’s criteria. Demographic data, hospitalization duration, PNI, CRP, and RDW levels were compared. Any p-value below 0.05 (p<0.05) was accepted as statistically significant. RESULTS: Study included 67 (51.15%) males and 64 (48.85%) females. The age average was 59.74 (19-90) years. 95 (72.52%) patients had MAP, and 36 (27.48%) patients had SAP. Mean hospitalization time, PNI, and CRP differed significantly between the two groups (p=0.010, p<0.05, p<0.05, respectively). The RDW (p=0.380) level difference was insignificant. For SAP prediction; the sensitivity, specificity and cut-off value according to Ranson code cut-off point for PNI were determined as 80.0% (95% CI:54.8-85.8), %72.2 (95% CI:70.5-87.5) and ≤45.6 (gr/L) + (mm3), respectively, and 94.7% (95% CI:57.8-87.9), %75.0 (95% CI:88.1-98.3) and >105,1 mg/L, respectively for CRP. CONCLUSION: PNI and CRP values (but not RDW values) were compatible with the disease severity determined by the Ranson criteria.
Keywords
Acute pancreatitis; prognostic nutritional index; C-reactive protein; red cell distribution width; Ranson's criteria; severity
Subject
Medicine and Pharmacology, Gastroenterology and Hepatology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
