Version 1
: Received: 30 October 2022 / Approved: 1 November 2022 / Online: 1 November 2022 (01:10:43 CET)
Version 2
: Received: 10 November 2022 / Approved: 14 November 2022 / Online: 14 November 2022 (01:12:17 CET)
How to cite:
Cosmin, B.; Marius, H.; Marvin, O.; Radu, D.; Klara, B.; Ioan, T.; Andreea, V.; Dan Alexandru, S.; Diana, B.; Daiana, C.; Alexandra, S.; Horatiu, S. A Novel Understanding of Serum Creatinine Levels as a Predictive Factor for Mortality Outcome in Aortic Disease. Preprints2022, 2022110003. https://doi.org/10.20944/preprints202211.0003.v1
Cosmin, B.; Marius, H.; Marvin, O.; Radu, D.; Klara, B.; Ioan, T.; Andreea, V.; Dan Alexandru, S.; Diana, B.; Daiana, C.; Alexandra, S.; Horatiu, S. A Novel Understanding of Serum Creatinine Levels as a Predictive Factor for Mortality Outcome in Aortic Disease. Preprints 2022, 2022110003. https://doi.org/10.20944/preprints202211.0003.v1
Cosmin, B.; Marius, H.; Marvin, O.; Radu, D.; Klara, B.; Ioan, T.; Andreea, V.; Dan Alexandru, S.; Diana, B.; Daiana, C.; Alexandra, S.; Horatiu, S. A Novel Understanding of Serum Creatinine Levels as a Predictive Factor for Mortality Outcome in Aortic Disease. Preprints2022, 2022110003. https://doi.org/10.20944/preprints202211.0003.v1
APA Style
Cosmin, B., Marius, H., Marvin, O., Radu, D., Klara, B., Ioan, T., Andreea, V., Dan Alexandru, S., Diana, B., Daiana, C., Alexandra, S., & Horatiu, S. (2022). A Novel Understanding of Serum Creatinine Levels as a Predictive Factor for Mortality Outcome in Aortic Disease. Preprints. https://doi.org/10.20944/preprints202211.0003.v1
Chicago/Turabian Style
Cosmin, B., Stoica Alexandra and Suciu Horatiu. 2022 "A Novel Understanding of Serum Creatinine Levels as a Predictive Factor for Mortality Outcome in Aortic Disease" Preprints. https://doi.org/10.20944/preprints202211.0003.v1
Abstract
Acute renal injury (AKI) is a complication that can occur after cardiac surgery, and sincetechnological advancements and knowledge in medicine are exponentially expanding, it requiresongoing research. The study aims to evaluate the outcome of the treated electives of emergencyaortic disease with high serum creatinine levels (SCr). Methods: The cohort included 183 patients, all of whom had an aortic disease and whose SCr levels were checked upon admission on the first day in the intensive care unit (ICU) and upon discharge from the hospital. We correlated SCr levels with in-hospital mortality and immediate mortality at least six months after discharge, with cross- clamp time and bypass time. Results: A high SCr level upon admission significantly predicts in- hospital mortality (p = 0.001) but not immediate mortality (p = 0.409). There is also a statistically significant correlation between the elevated SCr levels on the first day of ICU and aortic disease (p = 0.041) but not with immediate mortality (p = 0.119). We found a significant correlation between aortic disease and in-hospital mortality (p < 0.001) but no correlation between high SCr level on the first day of ICU and immediate mortality (p = 0.119). The cross-clamp time had a statistically significant correlation with elevated SCr level (p = 0.013) and in-hospital mortality (p = 0.001) but not with immediate mortality (p = 0.847). Furthermore, the bypass time was negatively correlated with a high SCr level on the first day of ICU (p = 0.090), with in-hospital mortality (p = 0.410) andimmediate mortality (p = 0.625). We also found that patients with an aortic disease were notcorrelated with elevated creatinine levels at ICU discharge (p = 0.152) or long-term mortality (p =0.106). Conclusions: The study only included a small portion of the elaborate surgical and medicalmanagement developed around cardiac patients who received invasive treatment. The conclusions 40 reached were nevertheless clearly relevant, evidenced by the significantly correlated statistics. Thiselement, moving forward, motivates us to expand our research’s range, collect the most newly relevant data, and use it to benefit the patient; this work provides the beginning step in this process.
Medicine and Pharmacology, Cardiac and Cardiovascular Systems
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.