Version 1
: Received: 13 October 2022 / Approved: 14 October 2022 / Online: 14 October 2022 (11:36:08 CEST)
How to cite:
Li, Y. Catalytic Hydrolysis of Organophosphorus 1 Nerve Agents by Metal-organic Frameworks: What Happens Next?. Preprints2022, 2022100212. https://doi.org/10.20944/preprints202210.0212.v1
Li, Y. Catalytic Hydrolysis of Organophosphorus 1 Nerve Agents by Metal-organic Frameworks: What Happens Next?. Preprints 2022, 2022100212. https://doi.org/10.20944/preprints202210.0212.v1
Li, Y. Catalytic Hydrolysis of Organophosphorus 1 Nerve Agents by Metal-organic Frameworks: What Happens Next?. Preprints2022, 2022100212. https://doi.org/10.20944/preprints202210.0212.v1
APA Style
Li, Y. (2022). Catalytic Hydrolysis of Organophosphorus 1 Nerve Agents by Metal-organic Frameworks: What Happens Next?. Preprints. https://doi.org/10.20944/preprints202210.0212.v1
Chicago/Turabian Style
Li, Y. 2022 "Catalytic Hydrolysis of Organophosphorus 1 Nerve Agents by Metal-organic Frameworks: What Happens Next?" Preprints. https://doi.org/10.20944/preprints202210.0212.v1
Abstract
Organophosphorus nerve agents are amongst the most toxic chemicals known to human beings. 9 They interfere with the central nervous system, resulting in continuous muscle contractions, 10 paralysis and even death. Prohibition by many countries around the world cannot disguise the 11 remaining presence of nerve agents in stockpile storage and governmental deployment, 12 highlighting the dire need for an efficient catalyst to degrade and detoxify nerve agents by 13 hydrolysis. Metal-organic frameworks (MOFs) have raised a few eyebrows for their permanent 14 porosity, precise tunability, and lasting stability. Modern Reticular Chemistry fosters the design and 15 synthesis of well-defined crystalline MOFs with open Lewis acidic metal sites that can catalytically 16 hydrolyze nerve agents both in aqueous solution and in solid state systems, unveiling unparalleled 17 potential for MOF-based personal protection gears. In this review, a summary of the representative 18 catalytically active MOFs in nerve agent hydrolysis is discussed. MOFs are categorized by their 19 reticular structure, emphasizing the capability and mechanistic insights of each single MOF in nerve 20 agent hydrolysis. The author’s perspective on the current challenges and future directions of MOF- 21 based catalysts in real-world protection applications is also provided, which hopefully could shed some 22 light on the future development of commercially available MOF protection suits.
Keywords
metal-organic frameworks; chemical warfare agents; catalytic hydrolysis
Subject
Chemistry and Materials Science, Applied Chemistry
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
