Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Usefulness of Skin Autofluorescence as a Biomarker of Oxidative Stress in Young Japanese Long-distance Runners: A Cross-Sectional Study

Version 1 : Received: 29 September 2022 / Approved: 30 September 2022 / Online: 30 September 2022 (07:30:22 CEST)

A peer-reviewed article of this Preprint also exists.

Fujiwara, R.; Anzai, N.; Ishikawa, M.; Takahashi, A. Usefulness of Skin Autofluorescence as a Biomarker of Acute Oxidative Stress in Young Male Japanese Long-Distance Runners: A Cross-Sectional Study. Sports 2022, 10, 180. Fujiwara, R.; Anzai, N.; Ishikawa, M.; Takahashi, A. Usefulness of Skin Autofluorescence as a Biomarker of Acute Oxidative Stress in Young Male Japanese Long-Distance Runners: A Cross-Sectional Study. Sports 2022, 10, 180.

Abstract

Chronic oxidative stress in long-distance runners adversely affects conditioning. Therefore, it is important to objectively assess and monitor oxidative stress but measuring oxidative stress can be invasive or require skill to measure. Therefore, this study aimed to verify whether skin autofluorescence (SAF), a noninvasive, rapid, and easily calculable metric for calculating advanced glycation end products (AGEs), is useful as an oxidative stress biomarker. The subjects were 50 young Japanese male long-distance runners (aged 20.2 ± 1.2 years); 35 average male university students (aged 19.8 ± 1.1 years) served as controls. The interactions and relationships between SAF and plasma pentosidine and oxidative stress markers (reactive oxygen metabolite-derived compounds [d-ROMs], biological antioxidant potential [BAP], and the BAP/d-ROMs ratio) in runners were examined, and SAF in the runners and controls was compared. The results suggest that plasma pentosidine in runners is associated with oxidative stress markers and that plasma pentosidine can assess oxidative stress. However, SAF was not validated as an oxidative stress marker because it was not associated with oxidative stress marker. In future, clarifying the factors affecting SAF may clarify the relationship between SAF, plasma pentosidine, and oxidative stress markers.

Keywords

advanced glycation end products; skin autofluorescence; pentosidine; d-ROMs; BAP; BAP/d-ROMs ratio; athlete; runner

Subject

Medicine and Pharmacology, Orthopedics and Sports Medicine

Comments (0)

We encourage comments and feedback from a broad range of readers. See criteria for comments and our Diversity statement.

Leave a public comment
Send a private comment to the author(s)
* All users must log in before leaving a comment
Views 0
Downloads 0
Comments 0
Metrics 0


×
Alerts
Notify me about updates to this article or when a peer-reviewed version is published.
We use cookies on our website to ensure you get the best experience.
Read more about our cookies here.