Version 1
: Received: 12 September 2022 / Approved: 14 September 2022 / Online: 14 September 2022 (04:37:05 CEST)
How to cite:
Naushad, T.; Türetgen, I.; Salim, S.; Sugathan, S. An In-vitro Study into the Inhibitory Effects of Etlingera elatior Flower Oil on Acinetobacter baumannii Biofilms. Preprints2022, 2022090191. https://doi.org/10.20944/preprints202209.0191.v1
Naushad, T.; Türetgen, I.; Salim, S.; Sugathan, S. An In-vitro Study into the Inhibitory Effects of Etlingera elatior Flower Oil on Acinetobacter baumannii Biofilms. Preprints 2022, 2022090191. https://doi.org/10.20944/preprints202209.0191.v1
Naushad, T.; Türetgen, I.; Salim, S.; Sugathan, S. An In-vitro Study into the Inhibitory Effects of Etlingera elatior Flower Oil on Acinetobacter baumannii Biofilms. Preprints2022, 2022090191. https://doi.org/10.20944/preprints202209.0191.v1
APA Style
Naushad, T., Türetgen, I., Salim, S., & Sugathan, S. (2022). An <em>In-vitro</em> Study into the Inhibitory Effects of <em>Etlingera </em><em>elatior </em>Flower Oil on <em>Acinetobacter baumannii </em>Biofilms. Preprints. https://doi.org/10.20944/preprints202209.0191.v1
Chicago/Turabian Style
Naushad, T., Sajna Salim and Shiburaj Sugathan. 2022 "An <em>In-vitro</em> Study into the Inhibitory Effects of <em>Etlingera </em><em>elatior </em>Flower Oil on <em>Acinetobacter baumannii </em>Biofilms" Preprints. https://doi.org/10.20944/preprints202209.0191.v1
Abstract
The current study investigates the antibiofilm properties of essential oil extracted from the Flower of a Zingiber plant used in traditional medicines. EO from Etlingera elatior (Jack) R. M Smith tested against one of the critical nosocomial pathogens, Acinetobacter baumannii. The antibiofilm studies of Flower essential oil (FEO) by crystal violet staining method exhibited maximum inhibition of 80% at a concentration of 0.7% oil. The biochemical assays and microscopic analysis showed that the FEO significantly reduced extracellular polymeric substance production. Furthermore, FEO reduced the survival rate of A. baumannii in human blood. The chemical composition of extracted FEO was analyzed by Gas chromatography- Mass spectrometry. Dodecanal, 1-dodecanol, and alpha-pinene were identified as the major compounds. Concerning previous research, our study is the first investigation of the antibiofilm property of E. elatior flower oil. More detailed studies are required to identify the compound responsible for biofilm inhibition and its mode of action against A. baumannii biofilms.
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
