Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

An In-vitro Study into the Inhibitory Effects of Etlingera elatior Flower Oil on Acinetobacter baumannii Biofilms

Version 1 : Received: 12 September 2022 / Approved: 14 September 2022 / Online: 14 September 2022 (04:37:05 CEST)

How to cite: Naushad, T.; Türetgen, I.; Salim, S.; Sugathan, S. An In-vitro Study into the Inhibitory Effects of Etlingera elatior Flower Oil on Acinetobacter baumannii Biofilms. Preprints 2022, 2022090191. https://doi.org/10.20944/preprints202209.0191.v1 Naushad, T.; Türetgen, I.; Salim, S.; Sugathan, S. An In-vitro Study into the Inhibitory Effects of Etlingera elatior Flower Oil on Acinetobacter baumannii Biofilms. Preprints 2022, 2022090191. https://doi.org/10.20944/preprints202209.0191.v1

Abstract

The current study investigates the antibiofilm properties of essential oil extracted from the Flower of a Zingiber plant used in traditional medicines. EO from Etlingera elatior (Jack) R. M Smith tested against one of the critical nosocomial pathogens, Acinetobacter baumannii. The antibiofilm studies of Flower essential oil (FEO) by crystal violet staining method exhibited maximum inhibition of 80% at a concentration of 0.7% oil. The biochemical assays and microscopic analysis showed that the FEO significantly reduced extracellular polymeric substance production. Furthermore, FEO reduced the survival rate of A. baumannii in human blood. The chemical composition of extracted FEO was analyzed by Gas chromatography- Mass spectrometry. Dodecanal, 1-dodecanol, and alpha-pinene were identified as the major compounds. Concerning previous research, our study is the first investigation of the antibiofilm property of E. elatior flower oil. More detailed studies are required to identify the compound responsible for biofilm inhibition and its mode of action against A. baumannii biofilms.

Keywords

Acinetobacter baumannii; Etlingera elatior; antibiofilm activity; essential oil

Subject

Biology and Life Sciences, Plant Sciences

Comments (0)

We encourage comments and feedback from a broad range of readers. See criteria for comments and our Diversity statement.

Leave a public comment
Send a private comment to the author(s)
* All users must log in before leaving a comment
Views 0
Downloads 0
Comments 0
Metrics 0


×
Alerts
Notify me about updates to this article or when a peer-reviewed version is published.
We use cookies on our website to ensure you get the best experience.
Read more about our cookies here.