Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Predictive Values of Nocturia and Its Voiding Frequency on the Aging Males’ Symptoms

Version 1 : Received: 28 July 2022 / Approved: 29 July 2022 / Online: 29 July 2022 (13:13:15 CEST)

A peer-reviewed article of this Preprint also exists.

Yuen, J.W.-M.; Wong, I.Y.-P.; Chiu, P.K.-F.; Teoh, J.Y.-C.; Chan, C.-K.; Yee, C.-H.; Ng, C.-F. Predictive Values of Nocturia and Its Voiding Frequency on the Aging Males’ Symptoms. Int. J. Environ. Res. Public Health 2022, 19, 11632. Yuen, J.W.-M.; Wong, I.Y.-P.; Chiu, P.K.-F.; Teoh, J.Y.-C.; Chan, C.-K.; Yee, C.-H.; Ng, C.-F. Predictive Values of Nocturia and Its Voiding Frequency on the Aging Males’ Symptoms. Int. J. Environ. Res. Public Health 2022, 19, 11632.

Abstract

Background: The link between nocturia and aging male symptoms (AMS) has not been scientifically established. This study aimed to measure the degree of severity of AMS that impact on the health-related quality-of-life (HRQoL) in adult males living with nocturia, and to determine the predictive values of nocturnal factors on AMS. Methods: It is an extended analysis of new data collected by using the Hong Kong Traditional AMS (HK-AMS) scale and Cantonese version of the Pittsburgh Sleep Quality Index (PSQI) in a recently published cross-sectional population-based survey. Results: Of the 781 respondents that have completed the set of questionnaires, 68% and 61% of men living with nocturia reported clinically significant (at moderate-to-severe levels) somato-vegetative and sexual AMS, whereas the prevalence and severity were increased with advancing nighttime voiding frequency. The nocturia-specific QoL (NQoL) score and nocturnal frequency were found to be significant predictive factors for composite, somato-vegetative and sexual AMS, in addition to age, global OSQI score, and certain metabolic diseases. Conclusions: Current findings suggested the inclusion of nocturia when measuring the male-specific HRQoL related to aging.

Keywords

Nocturia; aging male symptoms; Quality of life; Health-related Quality of life; Male adults; NQoL; Urinary frequency; Bedtime urination; sleep

Subject

Medicine and Pharmacology, Urology and Nephrology

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