Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

How Did Life Emerge in Chemically Complex Messy Environments?

Version 1 : Received: 27 June 2022 / Approved: 28 June 2022 / Online: 28 June 2022 (03:41:15 CEST)

A peer-reviewed article of this Preprint also exists.

Ikehara, K. How Did Life Emerge in Chemically Complex Messy Environments? Life 2022, 12, 1319. Ikehara, K. How Did Life Emerge in Chemically Complex Messy Environments? Life 2022, 12, 1319.

Abstract

One of the problems, which make it difficult to solve the mystery of the origin of life, would be how life emerged in chemically complex messy environments on the primitive Earth. It is considered that three main points contributed to open the way to the emergence of life. (1) A characteristic inherent in [GADV]-amino acids, which are easily produced with prebiotic means. (2) Protein 0th-order structure or [GADV]-amino acid composition generating water-soluble globular protein with some flexibility, which can be produced even by random joining of [GADV]-amino acids. (3) Formation of versatile [GADV]-microspheres, which can grow, divide, proliferate even without genetic system, was the emergence of proto-life. (4) [GADV]-microspheres with a higher proliferation ability than others could be selected. The proto-Dawin evolution made it possible to proceed forward to creation of the core life system composed of (GNC)n gene, anticodon stem-loop tRNA or AntiC-SL tRNA (GNC genetic code) and [GADV]-protein. (5) Eventually, the first genuine life with the core life system emerged. Thus, the formation processes of [GADV]-protein and (GNC)n gene in chemically complex messy environments were the steps to the emergence of genuine life.

Keywords

GADV hypothesis; origin of life; protein 0th-order structure; origin of protein; [GADV]-microsphere; origin of gene: the core life system

Subject

Biology and Life Sciences, Life Sciences

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