Review
Version 1
Preserved in Portico This version is not peer-reviewed
Biomechanics of Transcatheter Aortic Valve Implant
Version 1
: Received: 28 April 2022 / Approved: 29 April 2022 / Online: 29 April 2022 (13:10:19 CEST)
A peer-reviewed article of this Preprint also exists.
Nappi, F.; Avtaar Singh, S.S.; Nappi, P.; Fiore, A. Biomechanics of Transcatheter Aortic Valve Implant. Bioengineering 2022, 9, 299. Nappi, F.; Avtaar Singh, S.S.; Nappi, P.; Fiore, A. Biomechanics of Transcatheter Aortic Valve Implant. Bioengineering 2022, 9, 299.
Abstract
Transcatheter aortic valve implantation (TAVI) has grown exponentially within the cardiology and cardiac surgical spheres. It has now become a routine approach for treating aortic stenosis. Several uncertainties have been raised about TAVI in comparison to conventional surgical aortic valve replacement (SAVR). The primary concerns are with regards to the longevity of the valves. Several factors have been identified that may predict poor outcomes following TAVI. These include the lesser-used finite element analysis (FEA) to quantify the properties of calcifications that affect TAVI valves. This can also be used in conjunction with other integrated software to ascertain the functionality of these valves. Other imaging modalities are now widely available such as Multi-detector row computed tomography(MDCT) which can accurately size the aortic valve annulus.. This may help reduce the incidence of paravalvular leaks and regurgitation which may necessitate further intervention. Structural valve degeneration (SVD) remains a key factor with varying results from current studies. The true incidence of SVD in TAVI compared to SAVR remains unclear with the lack of long term data. It is now widely accepted that both are part of the armamentarium and are not mutually exclusive. Decision-making for the appropriate intervention should be made via shared decision-making involving the heart team.
Keywords
Transcatheter aortic valve implantation; Surgical aortic valve replacement; Structural valve degeneration; Transcatheter heart valves
Subject
Medicine and Pharmacology, Cardiac and Cardiovascular Systems
Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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