Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Sentinel Lymph Node in Breast Cancer: An Innovative Techniques

Version 1 : Received: 11 April 2022 / Approved: 14 April 2022 / Online: 14 April 2022 (10:51:37 CEST)

How to cite: Izzo, P.; Izzo, S.; Sibio, S.; Basso, L.; Polistena, A.; Raimondo, G.; Codacci-Pisanelli, M.; Gallo, G.; Messineo, D.; Izzo, L. Sentinel Lymph Node in Breast Cancer: An Innovative Techniques. Preprints 2022, 2022040132 (doi: 10.20944/preprints202204.0132.v1). Izzo, P.; Izzo, S.; Sibio, S.; Basso, L.; Polistena, A.; Raimondo, G.; Codacci-Pisanelli, M.; Gallo, G.; Messineo, D.; Izzo, L. Sentinel Lymph Node in Breast Cancer: An Innovative Techniques. Preprints 2022, 2022040132 (doi: 10.20944/preprints202204.0132.v1).

Abstract

(1) Background: Sentinel lymph node biopsy assumes importance in the search for metastases, especially in patients with malignant breast disease. Our study approaches the new techniques to prevent complications such as possible postoperative seroma formation, pain or hypoesthesia of the axillary cord and medial arm surface, as well as motor deficits in a preventive manner to avoid disabling outcomes and presents initial data from its experience with the sentinel lymph node biopsy technique. (2) Methods: There are mainly two radioactive tracer detection techniques and a new technique using a radiotracer called Sentimag-magtrace. The positive lymph node is located and removed to perform histologic analysis. In our study, we evaluate 100 patients who underwent breast cancer surgery (3) Results: our experience allowed us to calculate the identification rate with the different methods of sentinel lymph nodes by radioactive tracer 88.9 % vs magnetic tracer technology (Sendimag) 89.5%. (4) Conclusions Thus, this technique avoids radiation exposure for both patients and health care providers, as well as reducing costs and time.

Keywords

SLNB; SPIO; ALND; LS; superparamagnetic iron oxide nanoparticles

Subject

MEDICINE & PHARMACOLOGY, Oncology & Oncogenics

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