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Highly Efficient Synthesis of Benzimidazoles Using Microwave Irradiation

A peer-reviewed version of this preprint was published in:
Molecules 2022, 27(5), 1751. https://doi.org/10.3390/molecules27051751

Submitted:

09 February 2022

Posted:

10 February 2022

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Abstract
A microwave assisted method for synthesis of 2-substituted benzimidazoles has been developed. The combination of molar ratio N-phenyl-o-phenylenediamine:benzaldehyde (1:1) using microwave irradiation and only 1% mol of Er(OTf)3 provide an efficient, environmental and mild access to a diversity of benzimidazoles under solvent-free conditions.
Keywords: 
microwave
;  
green chemistry
;  
benzimidazoles
Subject: 
Chemistry and Materials Science  -   Organic Chemistry
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