Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Factors Associated With Chronic Kidney Disease in Patients With Type 2 Diabetes in Bangladesh

Version 1 : Received: 16 November 2021 / Approved: 19 November 2021 / Online: 19 November 2021 (09:26:12 CET)

A peer-reviewed article of this Preprint also exists.

Islam, S.M.S.; Salehin, M.; Zaman, S.B.; Tansi, T.; Gupta, R.D.; Barua, L.; Banik, P.C.; Uddin, R. Factors Associated with Chronic Kidney Disease in Patients with Type 2 Diabetes in Bangladesh. Int. J. Environ. Res. Public Health 2021, 18, 12277. Islam, S.M.S.; Salehin, M.; Zaman, S.B.; Tansi, T.; Gupta, R.D.; Barua, L.; Banik, P.C.; Uddin, R. Factors Associated with Chronic Kidney Disease in Patients with Type 2 Diabetes in Bangladesh. Int. J. Environ. Res. Public Health 2021, 18, 12277.

Journal reference: Int. J. Environ. Res. Public Health 2021, 18, 12277
DOI: 10.3390/ijerph182312277

Abstract

Diabetes and chronic kidney disease (CKD) are a major public health burden in low-and-middle-income countries. This study aimed to explore factors associated with CKD in patients with type 2 diabetes (T2D) in Bangladesh. A cross-sectional study was conducted among 315 adults with T2D presenting at the outpatient department of Bangladesh Institute of Health Sciences (BIHS) hospital between July 2013 to December 2013. CKD was diagnosed based on estimated Glomerular Filtration Rate using the ‘Modification of Diet in Renal Disease’ equations and presence of albuminuria estimated by the albumin-to-creatinine ratio. Multivariate logistic regression analysis was used to determine the factors associated with CKD. The overall prevalence of CKD among patients with T2D was 21.3%. In the unadjusted model Factors associated with CKD were: aged 40-49 years (OR: 5.7, 95% CI: 1.3-25.4), age 50-59 years (7.0, 1.6-39), age ≥60 years (7.6, 1.7-34); being female (2.2, 1.2-3.8), hypertensive (1.9, 1.1-3.5) and household income between 128.2-256.4 US$ (2.9, 1.0-8.2) compared with income ≤128.2$. However, after adjustment of other covariates, only duration of hypertension and household income (128.2-256.4 US$) remained statistically significant. There is a need to implement policies and programs for early detection and management of hypertension and CKD in T2D patients in Bangladesh.

Keywords

Type 2 Diabetes Mellitus; Chronic Kidney Diseases; Hypertension; Risk Factors; Bangladesh

Subject

MEDICINE & PHARMACOLOGY, General Medical Research

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