Preprint Review Version 2 Preserved in Portico This version is not peer-reviewed

Carbon-Based Materials in Photodynamic and Photothermal Therapies Applied to Tumor Destruction

Version 1 : Received: 30 October 2021 / Approved: 5 November 2021 / Online: 5 November 2021 (12:18:06 CET)
Version 2 : Received: 25 November 2021 / Approved: 26 November 2021 / Online: 26 November 2021 (11:10:10 CET)

A peer-reviewed article of this Preprint also exists.

Lagos, K.J.; Buzzá, H.H.; Bagnato, V.S.; Romero, M.P. Carbon-Based Materials in Photodynamic and Photothermal Therapies Applied to Tumor Destruction. Int. J. Mol. Sci. 2022, 23, 22. Lagos, K.J.; Buzzá, H.H.; Bagnato, V.S.; Romero, M.P. Carbon-Based Materials in Photodynamic and Photothermal Therapies Applied to Tumor Destruction. Int. J. Mol. Sci. 2022, 23, 22.

Journal reference: Int. J. Mol. Sci. 2021, 23, 22
DOI: 10.3390/ijms23010022

Abstract

Within phototherapy, a grand challenge in clinical cancer treatments is to develop a simple, cost-effective, and biocompatible approach to treat this disease using ultra-low doses of light. Carbon-based materials (CBM), such as graphene oxide (GO), reduced GO (r-GO), graphene quantum dots (GQDs), and carbon dots (C-DOTs), are rapidly emerging as a new class of thera-peutic materials against cancer. This mini-review summarizes the progress in lasts years re-garding the applications of CBM in photodynamic (PDT) and photothermal (PTT) therapies for tumor destruction. The current understanding of the performance of modified CBM, hybrids and composites, is also addressed. This approach seeks to achieve an enhanced healing action by im-proving and modulating the properties of CBM to treat various types of cancer. Metal oxides, organic molecules, biopolymers, therapeutic drugs, among others, have been combined with CBM to treat cancer by PDT, PTT, or synergistic therapies.

Keywords

phototherapy; cancer; graphene oxide; reduced graphene oxide; graphene quantum dots; carbon dots

Subject

LIFE SCIENCES, Biotechnology

Comments (1)

Comment 1
Received: 26 November 2021
Commenter: MARIA ROMERO
Commenter's Conflict of Interests: Author
Comment: More figures were placed, the English language was revised, the chapter was increased: "Advantages of CBM in PDT and PTT over organic and metal-organic PS". All changes are underlined in yellow.
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