Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Why and How to Use the Body’s Own Stem Cells for Regeneration in Musculoskeletal Disorders: A Primer

Version 1 : Received: 2 November 2021 / Approved: 3 November 2021 / Online: 3 November 2021 (16:16:42 CET)
Version 2 : Received: 11 November 2021 / Approved: 12 November 2021 / Online: 12 November 2021 (11:44:31 CET)

A peer-reviewed article of this Preprint also exists.

Journal reference: Journal of Orthopaedic Surgery and Research 2022, 17, 36
DOI: 10.1186/s13018-022-02918-8


Recently, the management of musculoskeletal disorders with the patients' own stem cells, isolated from the walls of small blood vessels, which can be found in great numbers in the adipose tissue, has received considerable attention. The use of these autologous, unmodified stem cells can be seamlessly integrated into modern orthopedic treatment concepts, which can be understood as the optimization of a process which - albeit less efficiently - also takes place physiologically. Accordingly, this new safe and effective type of treatment is attractive in terms of holistic thinking and personalized medicine.


adipose-derived regenerative cells; ADRCs; adipose-derived stem cells; ADSCs; bone regeneration, cartilage regeneration; efficacy; point of care treatment; stem cell; tendon healing without scar formation; tendon regeneration; vaPS cells


MEDICINE & PHARMACOLOGY, Sport Sciences & Therapy

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