Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

On the Relationship between Corneal Biomechanics, Macrostructure and Optical Properties

Version 1 : Received: 27 October 2021 / Approved: 28 October 2021 / Online: 28 October 2021 (15:24:20 CEST)

A peer-reviewed article of this Preprint also exists.

Ávila, F.J.; Marcellán, M.C.; Remón, L. On the Relationship between Corneal Biomechanics, Macrostructure, and Optical Properties. J. Imaging 2021, 7, 280. Ávila, F.J.; Marcellán, M.C.; Remón, L. On the Relationship between Corneal Biomechanics, Macrostructure, and Optical Properties. J. Imaging 2021, 7, 280.

Abstract

Optical properties of the cornea are responsible for correct vision, ultrastructure allows optical transparency and biomechanical properties governs the shape, elasticity or stiffness of the cor-nea affecting ocular integrity and intraocular pressure. Therefore, optical aberrations, corneal transparency, structure and biomechanics play a fundamental role in the optical quality of hu-man vision, ocular health and refractive surgery outcomes. However, the convergence of those properties is not yet reported at macroscopic scale within the hierarchical structure of the cornea. This work explores the relationships between biomechanics, structure and optical properties (corneal aberrations and optical density) at macrostructural level of the cornea through dual Placido-Scheimpflug imaging and air-puff tonometry systems in a healthy young adult popula-tion. Results showed convergence between optical transparency, corneal macrostructure and biomechanics.

Keywords

Keywords: Corneal Biomechanics; Corneal structure; Corneal Aberrations; Optical Density; Scheimpflug imaging; Ocular Response Analyzer.

Subject

Biology and Life Sciences, Biophysics

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