Golusda, L.; Kühl, A.A.; Siegmund, B.; Paclik, D. Extracellular Matrix Components as Diagnostic Tools in Inflammatory Bowel Disease. Biology2021, 10, 1024.
Golusda, L.; Kühl, A.A.; Siegmund, B.; Paclik, D. Extracellular Matrix Components as Diagnostic Tools in Inflammatory Bowel Disease. Biology 2021, 10, 1024.
Golusda, L.; Kühl, A.A.; Siegmund, B.; Paclik, D. Extracellular Matrix Components as Diagnostic Tools in Inflammatory Bowel Disease. Biology2021, 10, 1024.
Golusda, L.; Kühl, A.A.; Siegmund, B.; Paclik, D. Extracellular Matrix Components as Diagnostic Tools in Inflammatory Bowel Disease. Biology 2021, 10, 1024.
Abstract
Work from the last years indicate that the extracellular matrix (ECM) plays a direct role in vari-ous cellular processes including proliferation, migration and differentiation. Besides homeostat-ic processes, its regulatory function in inflammation becomes more and more evident. In in-flammation like inflammatory bowel disease, the ECM composition is constantly remodeled which can result in a structuring of fistulizing disease course. Thus, tracking early ECM changes might bear the potential to predict the disease course. In this review, we will provide an over-view of relevant diagnostic methods focusing on ECM changes.
Biology and Life Sciences, Immunology and Microbiology
Copyright:
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