Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Cardiometabolic Health Risks, Lifestyle Behaviours and Quality of Life in People with Early Psychosis – A Cross Sectional Study

Version 1 : Received: 10 August 2021 / Approved: 11 August 2021 / Online: 11 August 2021 (08:55:02 CEST)

How to cite: Meepring, S.; Gray, R.; Li, Y.; Ho, G.W.; Chien, W.T.; Bressington, D. Cardiometabolic Health Risks, Lifestyle Behaviours and Quality of Life in People with Early Psychosis – A Cross Sectional Study. Preprints 2021, 2021080243 (doi: 10.20944/preprints202108.0243.v1). Meepring, S.; Gray, R.; Li, Y.; Ho, G.W.; Chien, W.T.; Bressington, D. Cardiometabolic Health Risks, Lifestyle Behaviours and Quality of Life in People with Early Psychosis – A Cross Sectional Study. Preprints 2021, 2021080243 (doi: 10.20944/preprints202108.0243.v1).

Abstract

Introduction: People with schizophrenia have poor cardiometabolic health, with elevated 10-year cardiovascular disease risk (CVD-R) scores and poor quality of life (QOL). There is lack of understanding of these issues in early psychosis. Aims: To quantify CVD-R in people with early psychosis and profile their obesity prevalence, lifestyle behaviours and QOL. Secondary aim was to explore associations between lifestyle behaviours/treatment characteristics and CVD-R/QOL. Method:Baseline data from 81 RCT participants were used to profile cardiometabolic health risks (QRISK®3, BMI and waist circumference). Participants self-reported lifestyle behaviours and QOL. Relationships between modifiable treatment/lifestyle factors and QOL/CVD-R were explored using bivariate analyses. Results: Participants’ relative risk for CVD over 10 years was 1.93 times higher than healthy counterparts; 39% also had an obese BMI and physical QOL was poor. No significant associations were observed between CVD-R or QOL with treatment characteristics and lifestyle factors. Discussion: Despite positive lifestyle behaviours, participants had elevated CVD-R scores and poor physical health related QOL. Quantifying CVD-R with QRISK®3 may highlight the need for health promotion interventions. Implications for practice: Mental health professionals should be alert to elevated cardiometabolic health risks in early psychosis, particularly as these can occur in the context of relatively healthy lifestyle behaviours.

Keywords

Early Psychosis; Cardiovascular Disease Risk; Quality of Life; Lifestyle Behaviours.

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