Review
Version 1
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AMDV Vaccine: Challenges and Perspectives
Version 1
: Received: 2 August 2021 / Approved: 5 August 2021 / Online: 5 August 2021 (11:13:05 CEST)
A peer-reviewed article of this Preprint also exists.
Markarian, N.M.; Abrahamyan, L. AMDV Vaccine: Challenges and Perspectives. Viruses 2021, 13, 1833. Markarian, N.M.; Abrahamyan, L. AMDV Vaccine: Challenges and Perspectives. Viruses 2021, 13, 1833.
Abstract
Aleutian mink disease virus (AMDV) is known to cause the most significant disease in the mink industry. It is globally widespread and manifested as a deadly plasmacytosis and hyperglobulinemia. So far, measures to control viral spread have been limited to manual serological testing for AMDV-positive mink. Further, due to the persistent nature of this virus, attempts to eradicate Aleutian disease (AD) have largely failed. Therefore, effective strategies to control viral spread are of crucial importance for wildlife protection. One potentially key tool in the fight against this disease is by immunization of mink against AMDV. Throughout many years, several researchers have tried to develop AMDV vaccines and demonstrated varying degrees of protection in mink by those vaccines. Despite these attempts, there are currently no vaccines available against AMDV, allowing the continuation of the spread of Aleutian disease. Herein, we summarize previous AMDV immunization attempts in mink as well as other preventative measures with the purpose to shed light on future studies designing such a potentially crucial preventative tool against Aleutian disease.
Keywords
AMDV; Aleutian disease; mink parvovirus; Aleutian mink disease virus; vaccine
Subject
Biology and Life Sciences, Virology
Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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