Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Transporters Beam Signals from Cell Membranes

Version 1 : Received: 9 July 2021 / Approved: 12 July 2021 / Online: 12 July 2021 (11:24:18 CEST)

How to cite: Ristovski, M.; Farhat, D.; Bancud, S.; Lee, J. Transporters Beam Signals from Cell Membranes. Preprints 2021, 2021070244 (doi: 10.20944/preprints202107.0244.v1). Ristovski, M.; Farhat, D.; Bancud, S.; Lee, J. Transporters Beam Signals from Cell Membranes. Preprints 2021, 2021070244 (doi: 10.20944/preprints202107.0244.v1).

Abstract

Lipid composition in the cellular membranes plays an important role in maintaining the struc-tural integrity of cells and in regulating cellular signaling that controls functions of both mem-brane-anchored and cytoplasmic proteins. ATP-dependent ABC and P4-ATPase lipid transport-ers, two integral membrane proteins, are known to contribute to lipid translocation across the li-pid bilayers on the cellular membranes. In this review, we will highlight current knowledge about the role of cholesterol and phospholipids of cellular membrane in regulating cell signaling and how lipid transporters participate this process.

Subject Areas

P4-ATPase; ABC transporter; phospholipid; cholesterol; membranes; cellular signaling

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