Review
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Molecular Biology for Cancer Therapy: Review Articles
Version 1
: Received: 9 June 2021 / Approved: 10 June 2021 / Online: 10 June 2021 (11:39:26 CEST)
How to cite: goshu, B. Molecular Biology for Cancer Therapy: Review Articles. Preprints 2021, 2021060290. https://doi.org/10.20944/preprints202106.0290.v1 goshu, B. Molecular Biology for Cancer Therapy: Review Articles. Preprints 2021, 2021060290. https://doi.org/10.20944/preprints202106.0290.v1
Abstract
introduction: Cancer, as clusters of diseases, uncontrolled cell proliferation due to tumor suppressor genes inactivation, oncogenes activation, and external factors.Methods: To review data, electronic databases such as Nature, PubMed/PMC, Science Direct/Elsevier, EMBASE, and Google Scholar were used.Results: Derestricted forms of proto-oncogenes are oncogenes, which had vital roles in various paths of cell cycle modulation. Translocations and chromosomal rearrangement and/or mutations in genes are the major factors for the transformation of proto-oncogene to oncogenes. Herein, to prevent the proliferation of cancerous cells, oncogenes are targeted molecules. From a cancer therapeutic target point of view, oncogene silencing and deletion, mutation of tumor suppressor genes, and retroviral therapy molecular techniques were developed. Conclusion: To establish a cancer-free world, the most commonly used techniques are: Ribose Nucleic Acid interferences, zinc finger nucleases, and CRISPR.Keywords: Cancer, Oncogenes, Proto-oncogenes, molecular technique
Supplementary and Associated Material
Keywords
Cancer; Oncogenes; Proto-oncogenes; molecular technique
Subject
Medicine and Pharmacology, Oncology and Oncogenics
Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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