Preprint Brief Report Version 1 Preserved in Portico This version is not peer-reviewed

SCA Medium: A New Culture Medium for the Isolation of all Candida auris Clade

Version 1 : Received: 23 April 2021 / Approved: 26 April 2021 / Online: 26 April 2021 (11:06:41 CEST)

A peer-reviewed article of this Preprint also exists.

Ibrahim, A.; Peyclit, L.; Abdallah, R.; Khelaifia, S.; Chamieh, A.; Rolain, J.-M.; Bittar, F. SCA Medium: A New Culture Medium for the Isolation of all Candida auris Clades. J. Fungi 2021, 7, 433. Ibrahim, A.; Peyclit, L.; Abdallah, R.; Khelaifia, S.; Chamieh, A.; Rolain, J.-M.; Bittar, F. SCA Medium: A New Culture Medium for the Isolation of all Candida auris Clades. J. Fungi 2021, 7, 433.

Abstract

Candida auris is an emerging multidrug resistant yeast causing nosocomial infections and associated with high mortality in immunocompromised patients. Rapid identification and characterisation is necessary for its diagnosis and containing spread. In this study, we present a selective culture medium for all C. auris clades. This medium is sensitive with a limit of detection of 102 CFU/ml. The 100% specificity of SCA (Specific C. auris) medium is confirmed on a set of 134 Candida strains, 50 bacterial species and 200 human stool samples. Thus, this medium specifically selects for C. auris isolation from clinical samples, and allows studying its phenotypic profile.

Keywords

Candida; Candida auris; Culture; Emerging fungus; Isolation; Specific medium

Subject

Biology and Life Sciences, Biochemistry and Molecular Biology

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