Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Secure Air Traffic Control at the Hub of Multiplexing on the Centrifugo-Pneumatic Lab-on-a-Disc Platform

Version 1 : Received: 20 April 2021 / Approved: 22 April 2021 / Online: 22 April 2021 (14:07:56 CEST)

How to cite: Ducrée, J. Secure Air Traffic Control at the Hub of Multiplexing on the Centrifugo-Pneumatic Lab-on-a-Disc Platform. Preprints 2021, 2021040612 (doi: 10.20944/preprints202104.0612.v1). Ducrée, J. Secure Air Traffic Control at the Hub of Multiplexing on the Centrifugo-Pneumatic Lab-on-a-Disc Platform. Preprints 2021, 2021040612 (doi: 10.20944/preprints202104.0612.v1).

Abstract

Larger-scale integration (LSI) resides at the heart of comprehensive sample-to-answer automation and parallelisation of assay panels for frequent and ubiquitous bioanalytical testing in decentralised the point-of-use / point-of-care settings. With an emphasis on rotational, centrifugo-pneumatic flow control, this paper employs a virtual “digital twin” strategy, considering experimental tolerances, to efficiently design such “Lab-on-a-Disc” systems featuring high packing density, reliability, configurability, modularity, manufacturability, performance while minimizing development and fabrication cost.

Subject Areas

centrifugal microfluidics; Lab-on-a-Disc; centrifugo-pneumatic flow control; integration; multiplexing; parallelization; sample-to-answer; reliability; tolerances; design-for-manufacture; digital twin; event-triggering

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