García-Dorta, A.; Medina-Vega, L.; Villacampa-Jiménez, J.J.; Hernández-Díaz, M.; Bustabad-Reyes, S.; González-Dávila, E.; Díaz-González, F. Baseline Levels of Vitamin D in a Healthy Population from a Region with High Solar Irradiation. Nutrients2021, 13, 1647.
García-Dorta, A.; Medina-Vega, L.; Villacampa-Jiménez, J.J.; Hernández-Díaz, M.; Bustabad-Reyes, S.; González-Dávila, E.; Díaz-González, F. Baseline Levels of Vitamin D in a Healthy Population from a Region with High Solar Irradiation. Nutrients 2021, 13, 1647.
García-Dorta, A.; Medina-Vega, L.; Villacampa-Jiménez, J.J.; Hernández-Díaz, M.; Bustabad-Reyes, S.; González-Dávila, E.; Díaz-González, F. Baseline Levels of Vitamin D in a Healthy Population from a Region with High Solar Irradiation. Nutrients2021, 13, 1647.
García-Dorta, A.; Medina-Vega, L.; Villacampa-Jiménez, J.J.; Hernández-Díaz, M.; Bustabad-Reyes, S.; González-Dávila, E.; Díaz-González, F. Baseline Levels of Vitamin D in a Healthy Population from a Region with High Solar Irradiation. Nutrients 2021, 13, 1647.
Abstract
The use of vitamin D (VitD) supplements has become widespread in the last decade due not only to the dissociation between the blood levels recommended as "optimal" and those shown by the healthy population, but also to its presumed beneficial effects on multiple disorders. This work evaluated the levels of 25-hydroxyvitamin D [25(OH)D] in a healthy population of European origin living in a region with high solar irradiation. In serum samples from a population-based study conducted in the Canary Islands, levels of 25(OH)D were analyzed. In 876 individuals who had no history of kidney or malabsorption disorders and who had not been treated with calcium and/or VitD supplementation, the median 25(OH)D level was 26.3 (5th;95th percentile, 14.3;45.8)ng/mL. Notably, 65.4% of the population had 25(OH)D blood levels below 30ng/mL, 23.4% below 20ng/mL and 6.4% below 15ng/mL. Based on the lack of evidence supporting causality between 25(OH)D levels below what is recommended as optimal (≥20ng/mL, or even ≥30ng/mL) and major skeletal and non-skeletal diseases, and in light of the distribution of the concentration of this vitamin in healthy adults living under optimal conditions of solar irradiation, it seems reasonable to consider 25(OH)D levels below 20ng/mL and close to 15ng/mL as adequate for the general population.
Keywords
Vitamin D levels; population-based distribution; healthy adults; high solar irradiation.
Subject
Medicine and Pharmacology, Dietetics and Nutrition
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
