Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Current Challenges of Cardiac Amyloidosis Awareness Among Romanian Cardiologists

Version 1 : Received: 24 March 2021 / Approved: 25 March 2021 / Online: 25 March 2021 (15:16:31 CET)

A peer-reviewed article of this Preprint also exists.

Adam, R.; Neculae, G.; Stan, C.; Jurcut, R. Current Challenges of Cardiac Amyloidosis Awareness among Romanian Cardiologists. Diagnostics 2021, 11, 834. Adam, R.; Neculae, G.; Stan, C.; Jurcut, R. Current Challenges of Cardiac Amyloidosis Awareness among Romanian Cardiologists. Diagnostics 2021, 11, 834.

Journal reference: Diagnostics 2021, 11, 834
DOI: 10.3390/diagnostics11050834

Abstract

Cardiac amyloidosis (CA) is a restrictive cardiomyopathy characterized by deposition of amyloid in the myocardium and recent studies revealed it is more frequently seen than we thought. Advances have been made over the last years, but a delayed diagnosis is frequently seen. An online survey was conducted among cardiologists from Romania representing the first assessment of the knowledge of CA among them with 195 cardiologists answering the questionnaire. There was a wide variation in their knowledge regarding CA. Our participants had few experience with CA and reported a significant delay between first cardiac symptom and diagnosis. Around one half of them did not seem familiar with the noninvasive diagnostic algorithm and with the wild-type transthyretin amyloidosis (ATTRwt). Even the participants who are aware of this condition and the available treatment options stated this is a rare disease and there is no disease modifying treatment available for ATTRwt. Awareness among cardiologists is the most important challenge in diagnosing CA. Romanian cardiologists are partially aware of this topic, but there are still gaps in their knowledge. Educational programs can improve screening of patients with a high suspicion for this progressive condition whose evolution has been dramatically changed by the new treatment options.

Keywords

amyloidosis; cardiologist; awareness; survey; ATTR

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