Working Paper Article Version 1 This version is not peer-reviewed

Silver Nano Dots and Their Application in Bio Bar Code Assays and Medicine

Version 1 : Received: 25 January 2021 / Approved: 27 January 2021 / Online: 27 January 2021 (11:44:48 CET)
(This article belongs to the Research Topic Ecofriendly Materials)

How to cite: George, P. Silver Nano Dots and Their Application in Bio Bar Code Assays and Medicine. Preprints 2021, 2021010554 George, P. Silver Nano Dots and Their Application in Bio Bar Code Assays and Medicine. Preprints 2021, 2021010554

Abstract

Nano medicine seeks to deliver a valuable set of research tools and clinically useful devices in the near future. The current medical field is in dire need of new commercial applications in the pharmaceutical industry that may include advanced drug delivery systems, new therapies, and in vivo imaging. Here in this experimental study, the nano materials used in DNA biosensors like silver nano dots were incorporated as nano biosensors are used for both therapeutic and diagnostic applications. The most important step while preparing a DNA biosensor is the immobilization of DNA probe on the surface of a sensing device such as an electrode. The amount of immobilized DNA probe will influence the accuracy sensitivity, selectivity and life of a DNA biosensor directly. Because of the high surface to volume ratio and excellent biological compatibility, nano materials can enlarge the sensing surface area to increase the amount of immobilized DNA and the DNA mixed with nano materials can keep its biologically activity well.In this study,silver nano dots created in our lab were functionalized with thio nucleides and were used as nano sensor probes in bio bar code assays.

Subject Areas

Silver nano dots; DNA; Biobar code assays; nano sensors; nano medicine

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