Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Antiproliferative and Antimicrobial Activity of Anthocyanins after their Isolation and Freeze-Drying

Version 1 : Received: 23 December 2020 / Approved: 24 December 2020 / Online: 24 December 2020 (13:26:39 CET)

How to cite: Salamon, I.; Şimşek Sezer, E.N.; Kryvtsova, M.; Labun, P. Antiproliferative and Antimicrobial Activity of Anthocyanins after their Isolation and Freeze-Drying. Preprints 2020, 2020120623 (doi: 10.20944/preprints202012.0623.v1). Salamon, I.; Şimşek Sezer, E.N.; Kryvtsova, M.; Labun, P. Antiproliferative and Antimicrobial Activity of Anthocyanins after their Isolation and Freeze-Drying. Preprints 2020, 2020120623 (doi: 10.20944/preprints202012.0623.v1).

Abstract

Natural phytochemicals in foods, including anthocyanins, can play an important role in human health. Anthocyanins have been reported to cause many various useful effects, such as reducing cancer cell proliferation, regulating blood pressure, preventing tumour formation, improving eyesight, and preventing diabetes. In this study, we aimed to reveal the qualitative anthocyanin content, antiproliferative and antimicrobial effects of different extracts derived from Vaccinium myrtillus, V. corymbosum, Sambucus nigra and Aronia melanocarpa. The anthocyanin content of the plants mentioned in the study was characterized after the freeze-drying process. MTT assay was used to determine the antiproliferative effect of extracts on cancer cells. Antimicrobial effects of extracts were studied on typical and clinical strains of 5 different bacteria. As a result, the anthocyanin content in the extracts obtained was determined to be quite good with the freeze-drying method, and it was also determined that the extracts had various levels of antiproliferative and antibacterial effects.

Subject Areas

Antimicrobial; berries; cytotoxic; cyanidine; elderberry; lyophilization

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