Version 1
: Received: 20 December 2020 / Approved: 21 December 2020 / Online: 21 December 2020 (11:12:31 CET)
Version 2
: Received: 25 March 2021 / Approved: 25 March 2021 / Online: 25 March 2021 (15:14:06 CET)
Version 3
: Received: 14 November 2021 / Approved: 15 November 2021 / Online: 15 November 2021 (13:34:33 CET)
How to cite:
Marsellach, X. The Principle of Continuous Biological Information Flow as the Fundamental Foundation for the Biological Sciences. Implications for Ageing Research. Preprints2020, 2020120506. https://doi.org/10.20944/preprints202012.0506.v1
Marsellach, X. The Principle of Continuous Biological Information Flow as the Fundamental Foundation for the Biological Sciences. Implications for Ageing Research. Preprints 2020, 2020120506. https://doi.org/10.20944/preprints202012.0506.v1
Marsellach, X. The Principle of Continuous Biological Information Flow as the Fundamental Foundation for the Biological Sciences. Implications for Ageing Research. Preprints2020, 2020120506. https://doi.org/10.20944/preprints202012.0506.v1
APA Style
Marsellach, X. (2020). The Principle of Continuous Biological Information Flow as the Fundamental Foundation for the Biological Sciences. Implications for Ageing Research. Preprints. https://doi.org/10.20944/preprints202012.0506.v1
Chicago/Turabian Style
Marsellach, X. 2020 "The Principle of Continuous Biological Information Flow as the Fundamental Foundation for the Biological Sciences. Implications for Ageing Research" Preprints. https://doi.org/10.20944/preprints202012.0506.v1
Abstract
The current state of biological knowledge contains an unresolved paradox: life as a continuity in the face of the phenomena of ageing. In this manuscript I propose a theoretical framework that offers a solution for this apparent contradiction. The framework proposed is based on a rethinking of what ageing is at a molecular level, as well as on a rethinking of the mechanisms in charge of the flow of information from one generation to the following ones. I propose an information-based conception of ageing instead of the widely accepted damage-based conception of ageing and propose a full recovery of the chromosome theory of inheritance to describe the intergenerational flow of information. Altogether the proposed framework allows a precise and unique definition of what life is: a continuous flow of biological information. The proposed framework also implies that ageing is merely a consequence of the way in which epigenetically-coded phenotypic characteristics are passed from one generation to the next ones.
Keywords
Ageing; Epigenetics
Subject
Biology and Life Sciences, Biochemistry and Molecular Biology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.