Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

The Effectiveness of Therapeutic Physical Exercise in Patients with Amyotrophic Lateral Sclerosis in Relation to the Alsfrs-R Functionality Scale: A Systematic Review

Version 1 : Received: 18 November 2020 / Approved: 20 November 2020 / Online: 20 November 2020 (11:53:01 CET)

A peer-reviewed article of this Preprint also exists.

Ortega-Hombrados, L.; Molina-Torres, G.; Galán-Mercant , A.; Sánchez-Guerrero, E.; González-Sánchez, M.; Ruiz-Muñoz, M. Systematic Review of Therapeutic Physical Exercise in Patients with Amyotrophic Lateral Sclerosis over Time. Int. J. Environ. Res. Public Health 2021, 18, 1074. Ortega-Hombrados, L.; Molina-Torres, G.; Galán-Mercant , A.; Sánchez-Guerrero, E.; González-Sánchez, M.; Ruiz-Muñoz, M. Systematic Review of Therapeutic Physical Exercise in Patients with Amyotrophic Lateral Sclerosis over Time. Int. J. Environ. Res. Public Health 2021, 18, 1074.

Abstract

Background: to analyze the changes that a therapeutic physical exercise program is capable of causing in the functionality of patients suffering from ALS and in addition, to analyze the respiratory capacity. Methods: a systematic review of the PubMed, SCOPUS, Cochrane, SciELO, PEDro, CINAHL and MEDline databases is carried out. The information was filtered using the following MeSH terms: "Amyotrophic lateral sclerosis", "Physical Therapy", "Physical and Rehabilitation Medicine". Clinical trials published in the last 5 years were included in which one of the interventions was therapeutic physical exercise in patients with ALS, which included the ALSFRS-R as a result variable. Results: 10 clinical trials with a total of 421 patients were analyzed, of which 183 underwent rehabilitation with physical exercise and were part of the case group; the rest belong to the control group and their treatment was mostly passive. The observed trend is of a decrease of approximately 6 points in the ALSFRS-R scale at 6 months in the case groups; however, no behavior pattern was met in the controls. Conclusions: Therapeutic physical exercise could contribute to slow down the deterioration of the musculature of people with ALS, thus facilitating the performance of their daily activities.What do you want to do ?New mailCopy

Keywords

Amyotrophic lateral sclerosis; physical therapy; rehabilitation; exercise

Subject

Medicine and Pharmacology, Immunology and Allergy

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