Review
Version 1
Preserved in Portico This version is not peer-reviewed
Eukaryotic and Prokaryotic Microbiota Interactions
Version 1
: Received: 4 November 2020 / Approved: 5 November 2020 / Online: 5 November 2020 (10:27:41 CET)
A peer-reviewed article of this Preprint also exists.
Kodio, A.; Menu, E.; Ranque, S. Eukaryotic and Prokaryotic Microbiota Interactions. Microorganisms 2020, 8, 2018. Kodio, A.; Menu, E.; Ranque, S. Eukaryotic and Prokaryotic Microbiota Interactions. Microorganisms 2020, 8, 2018.
Abstract
The nature of the relationship between the communities of microorganisms making up the microbiota in and on a host body has been increasingly explored in recent years. Microorganisms, including bacteria, archaea, viruses, parasites, and fungi, have often long co-evolved with their hosts. In human, the structure and diversity of microbiota vary according to the host’s immunity, diet, environment, age, physiological and metabolic status, medical practices (e.g. antibiotic treatment), climate, season, and host genetics. The recent advent of next generation sequencing (NGS) technologies enhanced observational capacities and allowed for a better understanding of the relationship between distinct microorganisms within microbiota. The interaction between the host and their microbiota has become a field of research into microorganisms with therapeutic and preventive interest for public health applications. This review aims at assessing the current knowledge on interactions between prokaryotic and eukaryotic communities. After a brief description of the metagenomic methods used in the studies analysed, we summarise the findings of available publications describing the interaction between the bacterial communities and protozoa, helminths, and fungi, either in vitro, in experimental models, or in humans. Overall, we observed the existence of a beneficial effect in situations where some microorganisms can improve the health status of the host, while the presence of other microorganisms has been associated with pathologies, resulting in an adverse effect on human health.
Keywords
Microbiota; mycobiota; interactions; host; NGS; metagenomics; culturomics; metabarcoding
Subject
Biology and Life Sciences, Biochemistry and Molecular Biology
Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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