Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Dual-Task Effect on Cognitive and Body Function, β-amyloid Levels in Alzheimer's Dementia Patients: a Randomized Controlled Trial

Version 1 : Received: 30 October 2020 / Approved: 2 November 2020 / Online: 2 November 2020 (08:06:39 CET)

How to cite: Nam, S.M.; KIM, S. Dual-Task Effect on Cognitive and Body Function, β-amyloid Levels in Alzheimer's Dementia Patients: a Randomized Controlled Trial. Preprints 2020, 2020110001 (doi: 10.20944/preprints202011.0001.v1). Nam, S.M.; KIM, S. Dual-Task Effect on Cognitive and Body Function, β-amyloid Levels in Alzheimer's Dementia Patients: a Randomized Controlled Trial. Preprints 2020, 2020110001 (doi: 10.20944/preprints202011.0001.v1).

Abstract

The purpose of this study is to explore the effects of dual-task training, including cognitive tasks, on cognitive and bodily functioning and β-amyloid levels in Alzheimer's dementia patients. The subjects were 34 inpatients diagnosed with Alzheimer's dementia at a nursing hospital located in Gyeongsansi, South Korea. The patients were randomly divided into a dual-task group (n = 16) and a single-task group (n = 18). The dual-task group performed cognitive tasks at the same time as exercising tasks, while the single-task group performed only exercise tasks. Each group was trained for 30 minutes three times a week for eight weeks. The Mini-Mental State Examination was used to measure the patients’ cognitive function. Static and dynamic balance were measured to evaluate bodily functioning. Static balance was measured using Biorescue, while dynamic balance was measured using the Berg Balance Scale. Blood analysis was performed to measure levels of β-amyloid, which is known to cause Alzheimer's dementia. Both groups exhibited statistically significant improvements in gait function after the training (p < .05). The dual-task group exhibited statistically significant differences in cognitive function, static and dynamic balance function, and β-amyloid levels after training (p < .05). A significant difference was observed between the two groups (p < .05). Dual-task activities were found to be effective in improving cognitive and bodily functioning and reducing β-amyloid levels in Alzheimer's dementia patients. Therefore, dual-task training is thought to be an effective method of treating and preventing Alzheimer's dementia.

Subject Areas

Alzheimer’s Disease; Task Performance; Cognition; Human Activities; Amyloid Beta Protein; Dementia

Comments (0)

We encourage comments and feedback from a broad range of readers. See criteria for comments and our diversity statement.

Leave a public comment
Send a private comment to the author(s)
Views 0
Downloads 0
Comments 0
Metrics 0


×
Alerts
Notify me about updates to this article or when a peer-reviewed version is published.
We use cookies on our website to ensure you get the best experience.
Read more about our cookies here.