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The Association between Influenza Vaccination and the Risk of SARS-CoV-2 Infection, Severe Illness, and Death: A Systematic Review of the Literature

A peer-reviewed version of this preprint was published in:
International Journal of Environmental Research and Public Health 2020, 17(21), 7870. https://doi.org/10.3390/ijerph17217870

Submitted:

28 September 2020

Posted:

29 September 2020

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Preprints on COVID-19 and SARS-CoV-2
Abstract
We reviewed the association between seasonal influenza vaccination and the risk of SARS-CoV-2 infection or complicated illness or poor outcome (e.g. severe disease, need for hospitalization or ventilatory support, or death) among COVID-19 patients. None of the studies that were reviewed (n=12) found a significant increase in the risk of infection or in the illness severity or lethality, while some reported significantly inverse associations. Our findings support measures aimed at raising influenza vaccination coverage in the coming months.
Keywords: 
SARS-CoV-2
;  
influenza vaccine
;  
systematic review
;  
infection
;  
severity
;  
risk
Subject: 
Biology and Life Sciences  -   Biochemistry and Molecular Biology
Copyright: This open access article is published under a Creative Commons CC BY 4.0 license, which permit the free download, distribution, and reuse, provided that the author and preprint are cited in any reuse.