Preprint Article Version 1 This version is not peer-reviewed

Dietary Calcium Intake in a Cohort of Individuals Evaluated for Low Bone Mineral Density: A Multicentre Italian Study

Version 1 : Received: 21 July 2020 / Approved: 22 July 2020 / Online: 22 July 2020 (14:11:35 CEST)

How to cite: Cairoli, E.; Aresta, C.; Giovanelli, L.; Eller-Vainicher, C.; Migliaccio, S.; Giannini, S.; Giusti, A.; Marcocci, C.; Gonnelli, S.; Isaia, G.; Rossini, M.; Chiodini, I.; Di Stefano, M. Dietary Calcium Intake in a Cohort of Individuals Evaluated for Low Bone Mineral Density: A Multicentre Italian Study. Preprints 2020, 2020070531 (doi: 10.20944/preprints202007.0531.v1). Cairoli, E.; Aresta, C.; Giovanelli, L.; Eller-Vainicher, C.; Migliaccio, S.; Giannini, S.; Giusti, A.; Marcocci, C.; Gonnelli, S.; Isaia, G.; Rossini, M.; Chiodini, I.; Di Stefano, M. Dietary Calcium Intake in a Cohort of Individuals Evaluated for Low Bone Mineral Density: A Multicentre Italian Study. Preprints 2020, 2020070531 (doi: 10.20944/preprints202007.0531.v1).

Abstract

A low calcium intake is associated with an increased fracture risk. We assessed the dietary calcium intake in a cohort of Italian individuals evaluated for low bone mineral density (BMD). A 7-day food-frequency questionnaire was administered to 1793 individuals consecutively referred at a Centre of the Italian Society for Osteoporosis, Mineral Metabolism and Skeletal Diseases for low BMD. In 30.3% (544/1793) and 20.9% (374/1793) of subjects the calcium intake was inadequate ( <700 mg/day) and adequate (>1200 mg/day), respectively. Patients with calcium intake <700 mg/day showed a higher prevalence of diabetes mellitus, idiopathic hypercalciuria and food allergy/intolerance (8.1%, 5.1%, 7.2%, respectively) than patients with calcium intake >700 mg/day (5.3%, 3.0%, 4.1%, respectively, p<0.04 for all comparisons), also after adjusting for age, gender and BMI. In 30.3% of fractured subjects the calcium intake was <700 mg/day. In Italy, a low calcium intake is highly prevalent in individuals at risk for low BMD. Importantly, an inadequate calcium intake is highly prevalent even in patients with history of fragility fractures. Only about a fifth of patients at risk for low BMD reported an adequate calcium intake

Subject Areas

dietary calcium intake; osteoporosis; fractures

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