Working Paper Review Version 1 This version is not peer-reviewed

Xerostomia: An Overview

Version 1 : Received: 21 July 2020 / Approved: 22 July 2020 / Online: 22 July 2020 (09:44:12 CEST)

How to cite: Choi, J. Xerostomia: An Overview. Preprints 2020, 2020070507 Choi, J. Xerostomia: An Overview. Preprints 2020, 2020070507


Xerostomia is a subjective symptom of dry mouth resulting from various causes, including side effects of medication, systemic disorders, radiation, and Sjögren’s syndrome. Recently, the number of patients afflicted with xerostomia has increased due to an increase in the elderly population and patients on medication.; (2) Methods: A systematic approach is required to determine the etiology and management of xerostomia. This review summarizes recent literatures on the diagnosis and management of xerostomia.; (3) Results: A patient with xerostomia experiences difficulty in chewing, swallowing, speaking, tasting, and maintaining oral hygiene. Xerostomia and hyposalivation are uncomfortable side-effects in many patients. Assessing the function of the salivary gland is essential for selecting an appropriate treatment, improving symptoms, and preventing oral complications. Also, a more systematic approach is required to differentiate the subjective symptoms of the patient from the objective hyposalivation.; and (4) Conclusions: Although there is no standardized treatment for xerostomia, doctors need to endeavor and adapt the various treatments of xerostomia, to unearth the optimal treatment required for the patient.


Xerostomia; Dry mouth; Salivary hypofunction; Saliva


Medicine and Pharmacology, Dentistry and Oral Surgery

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