Preprint Short Note Version 1 Preserved in Portico This version is not peer-reviewed

CoV-GLUE: A Web Application for Tracking SARS-CoV-2 Genomic Variation

Version 1 : Received: 16 June 2020 / Approved: 18 June 2020 / Online: 18 June 2020 (06:24:20 CEST)

How to cite: Singer, J.; Gifford, R.; Cotten, M.; Robertson, D. CoV-GLUE: A Web Application for Tracking SARS-CoV-2 Genomic Variation. Preprints 2020, 2020060225 (doi: 10.20944/preprints202006.0225.v1). Singer, J.; Gifford, R.; Cotten, M.; Robertson, D. CoV-GLUE: A Web Application for Tracking SARS-CoV-2 Genomic Variation. Preprints 2020, 2020060225 (doi: 10.20944/preprints202006.0225.v1).

Abstract

Summary CoV-GLUE is an online web application for the interpretation and analysis of SARS-CoV-2 virus genome sequences, with a focus on amino acid sequence variation. It is based on the GLUE data-centric bioinformatics environment and provides a browsable database of amino acid replacements and coding region indels that have been observed in sequences from the pandemic. Users may also analyse their own SARS-CoV-2 sequences by submitting them to the web application to receive an interactive report containing visualisations of phylogenetic classification and highlighting genomic variation of potentially high impact, for example linked to primer mismatches.Availability and implementation Available at http://cov-glue.cvr.gla.ac.uk. Implemented using GLUE, an open source framework for the development of virus sequence data resources. Contact [email protected]

Supplementary and Associated Material

http://cov-glue.cvr.gla.ac.uk: CoV-GLUE web application

Subject Areas

SARS-CoV-2; web application; virus genome; lineage assignment; amino acids

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