Preprint Review Version 1 This version is not peer-reviewed

COVID-19: Recent Findings into Emerging Coronavirus

Version 1 : Received: 11 June 2020 / Approved: 14 June 2020 / Online: 14 June 2020 (03:06:15 CEST)

How to cite: Hezam, K.; Almansoub, H.A.M.M.; Saleh, F.A.; Almansob, Y.A.M.; Al-Mekhlafi, H.; AL-Yousofi, A.; Al-Gheethi, A.; Almezgagi, M.; Al-Shaebi, F.; Murshed, D. COVID-19: Recent Findings into Emerging Coronavirus. Preprints 2020, 2020060157 (doi: 10.20944/preprints202006.0157.v1). Hezam, K.; Almansoub, H.A.M.M.; Saleh, F.A.; Almansob, Y.A.M.; Al-Mekhlafi, H.; AL-Yousofi, A.; Al-Gheethi, A.; Almezgagi, M.; Al-Shaebi, F.; Murshed, D. COVID-19: Recent Findings into Emerging Coronavirus. Preprints 2020, 2020060157 (doi: 10.20944/preprints202006.0157.v1).

Abstract

The emergence of novel coronavirus (SARS-CoV-2) in marked as the highest pathogenic coronavirus that has crossed from the hosts to the human population in the twenty-first century. The spreading of COVID-19 in different chinese cities and around the world is travel-related viral spread with the unprecedented nosocomial outbreaks. It has also shown with high case-fatality rates, indeed to urgent prophylactic and therapeutic settings. Scientific advancements of the SARS-CoV-2 pandemic allowed for rapid progress to understand the epidemiology and pathogenesis of SARS-CoV-2. This review highlights the the genomic structure of SARS-CoV-2 with the proposed roles of genotype and phenotype of SARS-CoV-2 in pathogenesis and discuss recent results supporting treatment strategies of COVID-19 with a special focus on how these new insights may facilitate rational development of SARS-CoV-2 for targeted therapies in the future.

Subject Areas

novel coronavirus; SARS-CoV-2; COVID-19; pneumonia; Betacoronavirus; transmission

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