Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Advances in Research on the Relationship between Intestinal Flora and Myasthenia Gravis

Version 1 : Received: 22 May 2020 / Approved: 23 May 2020 / Online: 23 May 2020 (16:40:23 CEST)

How to cite: Wu, X.; Xu, Y.; Wang, Q.; Wei, Y.; Karim, M.R.; Wang, Y. Advances in Research on the Relationship between Intestinal Flora and Myasthenia Gravis. Preprints 2020, 2020050378 (doi: 10.20944/preprints202005.0378.v1). Wu, X.; Xu, Y.; Wang, Q.; Wei, Y.; Karim, M.R.; Wang, Y. Advances in Research on the Relationship between Intestinal Flora and Myasthenia Gravis. Preprints 2020, 2020050378 (doi: 10.20944/preprints202005.0378.v1).

Abstract

Human intestinal flora refers to a large and diverse microbial population present in the digestive tract of the human body, which plays a significant role in the establishment of human immune homeostasis and the normal function of the immune system. Myasthenia Gravis is an autoimmune disease of the neuromuscular junction, mainly involved in the anti-acetylcholine receptor antibody, cellular immune dependence, and complement1. At present, studies have found that the intestinal flora of Myasthenia Gravis is different from that of healthy people. Probiotic therapy has been shown effective in the experimental autoimmune Myasthenia Gravis animal models. This article reviews the relationship between intestinal flora and Myasthenia Gravis, to provide new ideas for further study of the pathogenesis and clinical treatment of Myasthenia Gravis.

Subject Areas

intestinal flora; myasthenia gravis; research progress; autoimmune disease; EAMG

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