Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

# A Quantitative Comparisons of $\beta$-Coronavirus Genomes and Their Associated Genes

Version 1 : Received: 27 April 2020 / Approved: 28 April 2020 / Online: 28 April 2020 (08:21:07 CEST)

How to cite: Hassan, S.S.; Rout, R.K. A Quantitative Comparisons of $\beta$-Coronavirus Genomes and Their Associated Genes. Preprints 2020, 2020040486 (doi: 10.20944/preprints202004.0486.v1). Hassan, S.S.; Rout, R.K. A Quantitative Comparisons of $\beta$-Coronavirus Genomes and Their Associated Genes. Preprints 2020, 2020040486 (doi: 10.20944/preprints202004.0486.v1).

## Abstract

A precise understanding of the genes and associated genomes of SARS-CoV2 is important for various reasons such as discovering origin of the virus and virulence and so on. A thorough descriptive understanding of the SARS-CoV2 genomes and other coronavirus of the beta-coronavirus genus is primarily important. In this article, a set of ten genomes of four CoVs and their associated genes are considered for this present study. A spatial representations of nucleotide bases including purine-pyrimidine representations of the different genes of the corresponding genomes are quantified using Hurst exponent, Shannon entropy and density estimation of different nucleotides including GC content, in order to draw a comparison and contrast among the ten genomes of different types of CoVs which include MERS, SARS-CoV, HKU1 (Human Coronavirus) and associated their genes.

## Keywords

SARS-CoV2; MERS; HKU1; Hurst exponent; Shannon entropy; Nucleotide Density; Purine-Pyrimidine representation

BIOLOGY, Other

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