Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

BCG Vaccination Strategy for Preventaion against COVID-19: Hype or Hope?

Version 1 : Received: 18 April 2020 / Approved: 19 April 2020 / Online: 19 April 2020 (13:55:50 CEST)

How to cite: Rajarshi, K.; Chatterjee, A.; Ray, S. BCG Vaccination Strategy for Preventaion against COVID-19: Hype or Hope?. Preprints 2020, 2020040351 (doi: 10.20944/preprints202004.0351.v1). Rajarshi, K.; Chatterjee, A.; Ray, S. BCG Vaccination Strategy for Preventaion against COVID-19: Hype or Hope?. Preprints 2020, 2020040351 (doi: 10.20944/preprints202004.0351.v1).

Abstract

The Bacillus Calmette-Guerin vaccine (BCG vaccine) designed to prevent tuberculosis in children has been shown to induce a trained immune response in the body to fight against bacteria as well as other parasites and viruses. This knowledge has been reciprocated to generate the idea that this vaccine can also offer protection against severe acute respiratory syndrome coronavirus-2 (SARS-COV-2). Some recent pre-print articles have highlighted that countries with mass BCG immunizations seems to have a lower incidence of coronavirus disease 2019 (COVID-19) compared to those without BCG immunization. There are yet no experimental proof of any such association and the world health organisation (WHO) is currently testing the theory with clinical trials on selected cohorts. Epidemiologists and other scientific experts has expressed both their hope and concern simultaneously regarding the success theory of BCG vaccination to prevent COVID-19. Though its still not verified in any way whether the BCG vaccination can actually prevent COVID-19 or not but we believe a thorough analytical research in this regard is indeed worth a shot.

Subject Areas

COVID-19; BCG immunization; SARS-CoV-2; immunity and tuberculosis

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